8OSH
AAA+ motor subunit ChlI of magnesium chelatase, pentamer spring-washer-like conformation
Summary for 8OSH
| Entry DOI | 10.2210/pdb8osh/pdb |
| EMDB information | 17153 |
| Descriptor | Magnesium-chelatase subunit ChlI (1 entity in total) |
| Functional Keywords | aaa+, magnesium chelatase, cyanobacteria, photosynthesis |
| Biological source | Nostoc sp. PCC 7120 = FACHB-418 |
| Total number of polymer chains | 5 |
| Total formula weight | 210629.65 |
| Authors | Shvarev, D.,Moeller, A. (deposition date: 2023-04-18, release date: 2023-09-06, Last modification date: 2023-11-29) |
| Primary citation | Shvarev, D.,Scholz, A.I.,Moeller, A. Conformational variability of cyanobacterial ChlI, the AAA+ motor of magnesium chelatase involved in chlorophyll biosynthesis. Mbio, 14:e0189323-e0189323, 2023 Cited by PubMed Abstract: Photosynthesis is an essential life process that relies on chlorophyll. In photosynthetic organisms, chlorophyll synthesis involves multiple steps and depends on magnesium chelatase. This enzyme complex is responsible for inserting magnesium into the chlorophyll precursor, but the molecular mechanism of this process is not fully understood. By using cryogenic electron microscopy and conducting functional analyses, we have discovered that the motor subunit ChlI of magnesium chelatase undergoes conformational changes in the presence of ATP. Our findings offer new insights into how energy is transferred from ChlI to the other components of magnesium chelatase. This information significantly contributes to our understanding of the initial step in chlorophyll biosynthesis and lays the foundation for future studies on the entire process of chlorophyll production. PubMed: 37737632DOI: 10.1128/mbio.01893-23 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.9 Å) |
Structure validation
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