8IHF

Cryo-EM structure of HCA2-Gi complex with MK6892

Summary for 8IHF

Entry DOI	10.2210/pdb8ihf/pdb
EMDB information	35443
Descriptor	Guanine nucleotide-binding protein G(i) subunit alpha-1, scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
Functional Keywords	gpcr, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	191902.34
Authors	Suzuki, S.,Nishikawa, K.,Suzuki, H.,Fujiyoshi, Y. (deposition date: 2023-02-22, release date: 2023-08-30, Last modification date: 2023-12-06)
Primary citation	Suzuki, S.,Tanaka, K.,Nishikawa, K.,Suzuki, H.,Oshima, A.,Fujiyoshi, Y. Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding. Nat Commun, 14:5899-5899, 2023 Cited by PubMed: 37736747 DOI: 10.1038/s41467-023-41650-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.97 Å)

Structure validation