PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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1WYW	Crystal Structure of SUMO1-conjugated thymine DNA glycosylase 分子名称: CHLORIDE ION, G/T mismatch-specific thymine DNA glycosylase, MAGNESIUM ION, ... 著者 Baba, D, Maita, N, Jee, J.G, Uchimura, Y, Saitoh, H, Sugasawa, K, Hanaoka, F, Tochio, H, Hiroaki, H, Shirakawa, M. 登録日 2005-02-17 公開日 2005-06-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of thymine DNA glycosylase conjugated to SUMO-1. Nature, 435, 2005
6OEQ	Cryo-EM structure of mouse RAG1/2 12RSS-PRC/23RSS-NFC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
6OEP	Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
6OEN	Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2020-02-26 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
6OER	Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
6OEO	Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
2W3O	Crystal structure of the human PNKP FHA domain in complex with an XRCC1-derived phosphopeptide 分子名称: BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, CALCIUM ION, DNA REPAIR PROTEIN XRCC1 著者 Oliver, A.W, Ali, A.A.E, Pearl, L.H. 登録日 2008-11-13 公開日 2009-02-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Specific Recognition of a Multiply Phosphorylated Motif in the DNA Repair Scaffold Xrcc1 by the Fha Domain of Human Pnk. Nucleic Acids Res., 37, 2009
8JYD	A genetically encoded sensor based on a bacterial DNA ligase 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase 著者 Chen, L. 登録日 2023-07-03 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A genetically encoded sensor To Be Published
2D07	Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase 分子名称: G/T mismatch-specific thymine DNA glycosylase, Ubiquitin-like protein SMT3B 著者 Baba, D, Maita, N, Jee, J.G, Uchimura, Y, Saitoh, H, Sugasawa, K, Hanaoka, F, Tochio, H, Hiroaki, H, Shirakawa, M. 登録日 2005-07-26 公開日 2006-06-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase J.Mol.Biol., 359, 2006
6T7F	RCR E3 ligase E2-Ubiquitin transthiolation intermediate 分子名称: 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ... 著者 Mabbitt, P.D, Virdee, S. 登録日 2019-10-21 公開日 2020-08-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity. Nat.Chem.Biol., 16, 2020
6DBR	Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS 分子名称: CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ... 著者 Wu, H, Liao, M, Ru, H, Mi, W. 登録日 2018-05-03 公開日 2018-08-01 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBI	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates 分子名称: CALCIUM ION, Forward strand of 12-RSS signal end, Forward strand of 23-RSS signal end, ... 著者 Wu, H, Liao, M, Ru, H, Mi, W. 登録日 2018-05-03 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6DBJ	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates 分子名称: CALCIUM ION, Forward stand of RSS signal end, Forward strand of coding flank, ... 著者 Wu, H, Liao, M, Ru, H, Mi, W. 登録日 2018-05-03 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
6V0V	Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0) 分子名称: CALCIUM ION, DNA (30-MER), V(D)J recombination-activating protein 1, ... 著者 Chen, X, Yang, W, Gellert, M. 登録日 2019-11-19 公開日 2020-01-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.61 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
7TJF	S. cerevisiae ORC bound to 84 bp ARS1 DNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA, 84 bp ARS1, ... 著者 Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. 登録日 2022-01-16 公開日 2023-01-18 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
8DMB	Structure of Desulfovirgula thermocuniculi IsrB (DtIsrB) in complex with omega RNA and target DNA 分子名称: MAGNESIUM ION, Ubiquitin-like protein SMT3,IsrB protein,monomeric superfolder Green Fluorescent Protein, non-target DNA, ... 著者 Seiichi, H, Kappel, K, Zhang, F. 登録日 2022-07-08 公開日 2022-10-19 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the OMEGA nickase IsrB in complex with omega RNA and target DNA. Nature, 610, 2022
5G4Q	H.pylori Beta clamp in complex with 5-chloroisatin 分子名称: 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA 著者 Pandey, P, Gourinath, S. 登録日 2016-05-16 公開日 2017-06-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
5G48	H.pylori Beta clamp in complex with Diflunisal 分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA 著者 Pandey, P, Gourinath, S. 登録日 2016-05-06 公開日 2017-06-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal. FEBS Lett., 591, 2017
6KHY	The crystal structure of AsfvAP:AG 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (AGCGTCACCGACGAGGC), DNA(AGCGTCACCGACGAGG), ... 著者 Chen, Y.Q, Gan, J.H. 登録日 2019-07-16 公開日 2020-06-03 実験手法 X-RAY DIFFRACTION (3.008 Å) 主引用文献 A unique DNA-binding mode of African swine fever virus AP endonuclease. Cell Discov, 6, 2020
2QHO	Crystal structure of the UBA domain from EDD ubiquitin ligase in complex with ubiquitin 分子名称: E3 ubiquitin-protein ligase EDD1, Ubiquitin 著者 Kozlov, G, Gehring, K. 登録日 2007-07-02 公開日 2007-09-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD. J.Biol.Chem., 282, 2007
3V8K	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with biotin 分子名称: BIOTIN, Biotin ligase 著者 Yap, M.Y, Pendini, N.R. 登録日 2011-12-23 公開日 2012-12-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
3V7R	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor 分子名称: (3aS,4S,6aR)-4-(5-{1-[4-(6-amino-9H-purin-9-yl)butyl]-1H-1,2,3-triazol-4-yl}pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one, Biotin ligase 著者 Yap, M.Y, Pendini, N.R. 登録日 2011-12-21 公開日 2012-12-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
3V8L	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with biotinyl-5'-AMP 分子名称: BIOTINYL-5-AMP, Biotin ligase 著者 Yap, M.Y. 登録日 2011-12-23 公開日 2012-12-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
3V7S	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor 0364 分子名称: 5-methyl-3-[4-(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-1,3-benzoxazol-2(3H)-one, Biotin ligase 著者 Yap, M.Y, Pendini, N.R. 登録日 2011-12-21 公開日 2012-04-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
4DQ2	Structure of staphylococcus aureus biotin protein ligase in complex with biotinol-5'-amp 分子名称: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, Biotin-[acetyl-CoA-carboxylase] ligase 著者 Wilce, M, Yap, M, Pendini, N, Soares de Costa, T, Polyak, S, Tieu, W, Booker, G, Wallace, J. 登録日 2012-02-14 公開日 2012-04-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012

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