3V8L

Crystal structure of Staphylococcus aureus biotin protein ligase in complex with biotinyl-5'-AMP

Summary for 3V8L

Entry DOI	10.2210/pdb3v8l/pdb
Related	1HXD 2CGH 2EAY 3V7C 3V7R 3V7S 3V8J 3V8K
Descriptor	Biotin ligase, BIOTINYL-5-AMP (3 entities in total)
Functional Keywords	biotin, metabolism, biotin carboxyl carrier protein, ligase-ligase inhibitor complex, ligase/ligase inhibitor
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	38588.35
Authors	Yap, M.Y. (deposition date: 2011-12-23, release date: 2012-12-26, Last modification date: 2024-03-20)
Primary citation	Soares da Costa, T.P.,Tieu, W.,Yap, M.Y.,Pendini, N.R.,Polyak, S.W.,Sejer Pedersen, D.,Morona, R.,Turnidge, J.D.,Wallace, J.C.,Wilce, M.C.,Booker, G.W.,Abell, A.D. Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287:17823-17832, 2012 Cited by PubMed: 22437830 DOI: 10.1074/jbc.M112.356576 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation