4TNY
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![BU of 4tny by Molmil](/molmil-images/mine/4tny) | Structural basis of cellular dNTP regulation, SAMHD1-dGTP-dATP-dGTP complex | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | 著者 | Ji, X, Tang, C, Zhao, Q, Wang, W, Xiong, Y. | 登録日 | 2014-06-05 | 公開日 | 2014-10-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of cellular dNTP regulation by SAMHD1. Proc.Natl.Acad.Sci.USA, 111, 2014
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2H0M
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2H14
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2GPP
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![BU of 2gpp by Molmil](/molmil-images/mine/2gpp) | Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic ligand GSK4716 | 分子名称: | 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE, Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1 | 著者 | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | 登録日 | 2006-04-18 | 公開日 | 2006-09-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem., 281, 2006
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2HGL
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2LEH
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![BU of 2leh by Molmil](/molmil-images/mine/2leh) | Solution structure of the core SMN-Gemin2 complex | 分子名称: | Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 | 著者 | Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. | 登録日 | 2011-06-15 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the core SMN-Gemin2 complex. Biochem.J., 445, 2012
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2L5F
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2L4Z
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![BU of 2l4z by Molmil](/molmil-images/mine/2l4z) | NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82) | 分子名称: | DNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION | 著者 | Liew, C, Stokes, P.H, Kwan, A.H, Matthews, J.M. | 登録日 | 2010-10-22 | 公開日 | 2011-10-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8. J.Mol.Biol., 425, 2013
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2LA6
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![BU of 2la6 by Molmil](/molmil-images/mine/2la6) | Solution NMR Structure of RRM domain of RNA-binding protein FUS from homo sapiens, Northeast Structural Genomics Consortium Target HR6430A | 分子名称: | RNA-binding protein FUS | 著者 | Liu, G, Xiao, R, Janjua, H, Ciccosanti, C, Wang, H, Lee, H, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-03-04 | 公開日 | 2011-05-04 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Northeast Structural Genomics Consortium Target HR6430A To be Published
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2HVZ
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![BU of 2hvz by Molmil](/molmil-images/mine/2hvz) | Solution structure of the RRM domain of SR rich factor 9G8 | 分子名称: | Splicing factor, arginine/serine-rich 7 | 著者 | Tintaru, A.M, Hautbergue, G.M, Golovanov, A.P, Lian, L.Y, Wilson, S.A. | 登録日 | 2006-07-31 | 公開日 | 2006-11-21 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8. Embo J., 25, 2006
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2JZX
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![BU of 2jzx by Molmil](/molmil-images/mine/2jzx) | PCBP2 KH1-KH2 domains | 分子名称: | Poly(rC)-binding protein 2 | 著者 | Du, Z, Fenn, S, Tjhen, R, James, T. | 登録日 | 2008-01-21 | 公開日 | 2008-08-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the first and second KH domains of human poly-C binding protein-2 reveals insights into its regulatory mechanisms To be Published
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2K0B
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![BU of 2k0b by Molmil](/molmil-images/mine/2k0b) | NMR structure of the UBA domain of p62 (SQSTM1) | 分子名称: | Sequestosome-1 | 著者 | Long, J.E, Ciani, B, Gallagher, T.R.A, Cavey, J.R, Sheppard, P.W, Layfield, R, Searle, M.S. | 登録日 | 2008-01-31 | 公開日 | 2008-02-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformation and dynamics of the three-helix bundle UBA domain of p62 from experiment and simulation. Proteins, 71, 2007
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2JV3
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2L2L
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2LF7
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2KZU
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![BU of 2kzu by Molmil](/molmil-images/mine/2kzu) | DAXX helical bundle (DHB) domain / Rassf1C complex | 分子名称: | Death-associated protein 6, Ras association (RalGDS/AF-6) domain family 1 | 著者 | Escobar-Cabrera, E, Lau, D.K.W, Giovinazzi, S, Ishov, A.M, McIntosh, L.P. | 登録日 | 2010-06-25 | 公開日 | 2010-12-15 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C. Structure, 18, 2010
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2LGT
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![BU of 2lgt by Molmil](/molmil-images/mine/2lgt) | Backbone 1H, 13C, and 15N Chemical Shift Assignments for QFM(Y)F | 分子名称: | Eukaryotic peptide chain release factor subunit 1 | 著者 | Wong, L.E, Li, Y, Pillay, S, Pervushin, K. | 登録日 | 2011-08-02 | 公開日 | 2012-03-14 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1 Nucleic Acids Res., 2012
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2LLX
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2L3R
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![BU of 2l3r by Molmil](/molmil-images/mine/2l3r) | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Histone H3 peptide | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Histone H3 | 著者 | Nady, N, Lemak, A, Fares, C, Gutmanas, A, Avvakumov, G, Xue, S, Arrowsmith, C, Structural Genomics Consortium (SGC) | 登録日 | 2010-09-21 | 公開日 | 2011-04-13 | 最終更新日 | 2020-02-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein. J.Biol.Chem., 286, 2011
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2LD7
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![BU of 2ld7 by Molmil](/molmil-images/mine/2ld7) | Solution structure of the mSin3A PAH3-SAP30 SID complex | 分子名称: | Histone deacetylase complex subunit SAP30, Paired amphipathic helix protein Sin3a | 著者 | Xie, T, He, Y, Korkeamaki, H, Zhang, Y, Imhoff, R, Lohi, O, Radhakrishnan, I. | 登録日 | 2011-05-16 | 公開日 | 2011-06-15 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the 30-kDa Sin3-associated protein (SAP30) in complex with the mammalian Sin3A corepressor and its role in nucleic acid binding. J.Biol.Chem., 286, 2011
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6DO2
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![BU of 6do2 by Molmil](/molmil-images/mine/6do2) | Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine | 分子名称: | 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Endoplasmic reticulum chaperone BiP | 著者 | Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. | 登録日 | 2018-06-08 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of human GRP78 in complex with 7-deaza-2'-C-methyladenosine To Be Published
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6DQ4
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![BU of 6dq4 by Molmil](/molmil-images/mine/6dq4) | LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR GSK-J1 | 分子名称: | 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Horton, J.R, Cheng, X. | 登録日 | 2018-06-10 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.392 Å) | 主引用文献 | Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. J. Med. Chem., 61, 2018
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8G9Q
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![BU of 8g9q by Molmil](/molmil-images/mine/8g9q) | Tricomplex of Compound-1, KRAS G12C, and CypA | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Tomlinson, A.C.A, Chen, A, Knox, J.E, Yano, J.K. | 登録日 | 2023-02-21 | 公開日 | 2023-08-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS. Science, 381, 2023
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6DFM
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![BU of 6dfm by Molmil](/molmil-images/mine/6dfm) | Crystal structure of human GRP78 in complex with 8-aminoadenosine | 分子名称: | (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, Endoplasmic reticulum chaperone BiP | 著者 | Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. | 登録日 | 2018-05-15 | 公開日 | 2019-05-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of human GRP78 in complex with 8-aminoadenosine To be Published
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6DW7
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![BU of 6dw7 by Molmil](/molmil-images/mine/6dw7) | SAMHD1 without Catalytic Nucleotides | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GLYCINE, ... | 著者 | Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. | 登録日 | 2018-06-26 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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