Solution structure of the core SMN-Gemin2 complex

Summary for 2LEH

DescriptorSurvival of motor neuron protein-interacting protein 1, Survival motor neuron protein (2 entities in total)
Functional Keywordsspinal muscular atrophy, snrnp assembly, protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus, gem O14893
Cytoplasm Q16637
Total number of polymer chains2
Total molecular weight24472.51
Sarachan, K.L.,Valentine, K.,Gupta, K.,Moorman, V.,Gledhill, J.,Bernens, M.,Tommos, C.,Wand, A.J.,Van Duyne, G. (deposition date: 2011-06-15, release date: 2012-06-27, Last modification date: 2012-07-11)
Primary citation
Sarachan, K.L.,Valentine, K.G.,Gupta, K.,Moorman, V.R.,Gledhill Jr, J.M.,Bernens, M.,Tommos, C.,Wand, A.J.,Van Duyne, G.D.
Solution structure of the core SMN-Gemin2 complex.
Biochem.J., 445:361-370, 2012
PubMed: 22607171 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20120241
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers13 3.2% 4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
PDB entries from 2020-12-02