2LF7
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436
Summary for 2LF7
| Entry DOI | 10.2210/pdb2lf7/pdb |
| Related | 2LF8 |
| NMR Information | BMRB: 17741 |
| Descriptor | Transcription factor ETV6 (1 entity in total) |
| Functional Keywords | auto-inhibition, transcription |
| Biological source | Mus musculus (mouse) |
| Cellular location | Nucleus (By similarity): P97360 |
| Total number of polymer chains | 1 |
| Total formula weight | 13060.99 |
| Authors | Coyne III, H.,Green, S.M.,Graves, B.J.,Mcintosh, L.P. (deposition date: 2011-06-28, release date: 2012-05-23, Last modification date: 2023-06-14) |
| Primary citation | Coyne, H.J.,De, S.,Okon, M.,Green, S.M.,Bhachech, N.,Graves, B.J.,McIntosh, L.P. Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain. J.Mol.Biol., 421:67-84, 2012 Cited by PubMed: 22584210DOI: 10.1016/j.jmb.2012.05.010 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
Download full validation report
