2L2L
Solution structure of the coiled-coil complex between MBD2 and p66alpha
Summary for 2L2L
| Entry DOI | 10.2210/pdb2l2l/pdb |
| NMR Information | BMRB: 17138 |
| Descriptor | Transcriptional repressor p66-alpha, Methyl-CpG-binding domain protein 2 (2 entities in total) |
| Functional Keywords | dna methylation, coiled-coil, nurd, mbd2, p66alpha, transferase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 9297.80 |
| Authors | Williams Jr., D.C.,Scarsdale Jr., N. (deposition date: 2010-08-20, release date: 2011-05-04, Last modification date: 2020-02-05) |
| Primary citation | Gnanapragasam, M.N.,Scarsdale, J.N.,Amaya, M.L.,Webb, H.D.,Desai, M.A.,Walavalkar, N.M.,Wang, S.Z.,Zu Zhu, S.,Ginder, G.D.,Williams, D.C. p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex. Proc.Natl.Acad.Sci.USA, 108:7487-7492, 2011 Cited by PubMed: 21490301DOI: 10.1073/pnas.1015341108 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
Download full validation report
