NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82)

Summary for 2L4Z

Related1M3V 1RUT
DescriptorDNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION (2 entities in total)
Functional Keywordslim domain, protein-protein interaction, lim-interaction domain, lmo4, rbbp8/ctip, lim-only protein, hydrolase, metal binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight13350.62
Liew, C.,Stokes, P.H.,Kwan, A.H.,Matthews, J.M. (deposition date: 2010-10-22, release date: 2011-10-26, Last modification date: 2020-01-01)
Primary citation
Stokes, P.H.,Liew, C.W.,Kwan, A.H.,Foo, P.,Barker, H.E.,Djamirze, A.,O'Reilly, V.,Visvader, J.E.,Mackay, J.P.,Matthews, J.M.
Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8.
J.Mol.Biol., 425:1101-1110, 2013
PubMed: 23353824 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2013.01.017
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers10 2.9% 45.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
PDB entries from 2020-11-25