2L4Z

NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA endonuclease RBBP8,LIM domain transcription factor LMO4	polymer	123	13219.8	1	UniProt (Q99708) UniProt (P61969) Pfam (PF00412) In PDB	Homo sapiens (human)	CtBP-interacting protein,CtIP,Retinoblastoma-binding protein 8,RBBP-8,Retinoblastoma-interacting protein and myosin-like,RIM,Sporulation in the absence of SPO11 protein 2 homolog,SAE2,Breast tumor autoantigen,LIM domain only protein 4,LMO-4
2	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 641 - 685 (UniProt: Q99708)

PDB	External Database	Details
Gly 639	-	expression tag
Ser 640	-	expression tag
Gly 901	-	linker
Gly 902	-	linker
Ser 903	-	linker
Gly 904	-	linker
Gly 905	-	linker
His 906	-	linker
Met 907	-	linker
Gly 908	-	linker
Ser 909	-	linker
Gly 910	-	linker
Gly 911	-	linker

A: 18 - 82 (UniProt: P61969)

PDB	External Database	Details
Ser 52	Cys 52	engineered mutation
Ser 64	Cys 64	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13219.8
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	13350.6

*Water molecules are not included.