PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

---

8T69	Human VMAT2 in complex with tetrabenazine 分子名称: Synaptic vesicular amine transporter, tetrabenazine 著者 Pidathala, S, Dai, Y, Lee, C.H. 登録日 2023-06-15 公開日 2023-11-01 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Mechanisms of neurotransmitter transport and drug inhibition in human VMAT2. Nature, 623, 2023
8T67	Influenza PA-N Endonuclease I38T Mutant (amino acids 52-74 truncation) 分子名称: MANGANESE (II) ION, Polymerase acidic protein 著者 Kohlbrand, A.J, Cohen, S.M. 登録日 2023-06-15 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants. Biochemistry, 63, 2024
8T66	cA6 bound Cam1 分子名称: Cam1, RNA (5'-R(P*AP*AP*AP*AP*A)-3') 著者 Yu, Y, Patel, D.J. 登録日 2023-06-15 公開日 2024-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
8T65	cA4 bound Cam1 分子名称: Cam1, RNA (5'-R(P*AP*AP*AP*A)-3') 著者 Yu, Y, Patel, D.J. 登録日 2023-06-15 公開日 2024-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
8T64	Apo Cam1(42-206) 分子名称: Cam1 著者 Yu, Y, Patel, D.J. 登録日 2023-06-15 公開日 2024-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
8T63	Solution NMR structure of designed peptide PH1 (WHMWNTVPNAKQVIAA) 分子名称: Designed peptide PH1 著者 McShan, A.C, Torres, M.P. 登録日 2023-06-15 公開日 2023-06-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Generative beta-hairpin design using a residue-based physicochemical property landscape. Biophys.J., 2024
8T62	Solution NMR structure of designed peptide BH21 (TMIEDPEAGHFHTSSA) 分子名称: Designed peptide BH21 著者 McShan, A.C, Torres, M.P. 登録日 2023-06-15 公開日 2023-06-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Generative beta-hairpin design using a residue-based physicochemical property landscape. Biophys.J., 2024
8T61	Solution NMR structure of designed peptide BH33 (RHYYKFNSTGRHYHYY) 分子名称: Designed peptide BH33 著者 McShan, A.C, Torres, M.P. 登録日 2023-06-15 公開日 2023-06-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Generative beta-hairpin design using a residue-based physicochemical property landscape. Biophys.J., 2024
8T60	CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation 分子名称: Melibiose permease, NabFab_H Chain, NabFab_L Chain, ... 著者 Guan, L. 登録日 2023-06-14 公開日 2024-02-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter. Elife, 12, 2024
8T5Z	Influenza PA-N Endonuclease (amino acids 52-74 truncation) 分子名称: MANGANESE (II) ION, Polymerase acidic protein 著者 Kohlbrand, A.J, Cohen, S.M. 登録日 2023-06-14 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants. Biochemistry, 63, 2024
8T5Y	Structure of Rhodococcus sp. USK13 DarR(K44A)-cAMP complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DarR 著者 Schumacher, M.A. 登録日 2023-06-14 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding. Nat Commun, 14, 2023
8T5X	Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T) 分子名称: Transthyretin 著者 Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E. 登録日 2023-06-14 公開日 2023-08-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant. J.Am.Chem.Soc., 146, 2024
8T5W	Influenza PAN endonuclease I38T mutant with Baloxavir 分子名称: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Kohlbrand, A.J, Cohen, S.M. 登録日 2023-06-14 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants. Biochemistry, 63, 2024
8T5U	ATP-1 state of Bcs1 (C7 symmetrized) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 著者 Zhan, J, Xia, D. 登録日 2023-06-14 公開日 2024-06-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
8T5T	Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Borrelia burgdorferi (steric acid bound) 分子名称: Outer membrane lipoprotein carrier protein (LolA), STEARIC ACID, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-06-14 公開日 2023-06-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Borrelia burgdorferi (steric acid bound) To be published
8T5S	Cryo-EM structure of DRH-1 helicase and C-terminal domain bound to dsRNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dicer-related helicase, MAGNESIUM ION, ... 著者 Consalvo, C.D, Donelick, H.M, Shen, P.S, Bass, B.L. 登録日 2023-06-14 公開日 2024-05-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Caenorhabditis elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. Elife, 13, 2024
8T5R	SOS2 crystal structure with fragment bound (compound 13) 分子名称: 4-(aminomethyl)benzene-1-sulfonamide, SULFATE ION, Son of sevenless homolog 2 著者 Gunn, R.J, Lawson, J.D, Ivetac, A, Ulaganathan, T, Coulombe, R, Fethiere, J. 登録日 2023-06-14 公開日 2024-01-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. J.Med.Chem., 67, 2024
8T5Q	SARS-CoV-2 ORF3a peptide in complex with TRAF2 TRAF domain 分子名称: DI(HYDROXYETHYL)ETHER, ORF3a protein, TETRAETHYLENE GLYCOL, ... 著者 Busscher, B.M, Xiao, T.S. 登録日 2023-06-14 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 SARS-CoV-2 ORF3a-Mediated NF-kappa B Activation Is Not Dependent on TRAF-Binding Sequence. Viruses, 15, 2023
8T5P	SARS-CoV-2 ORF3a peptide in complex with TRAF3 TRAF domain 分子名称: ORF3a protein, TNF receptor-associated factor 3 著者 Busscher, B.M, Xiao, T.S. 登録日 2023-06-14 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 SARS-CoV-2 ORF3a-Mediated NF-kappa B Activation Is Not Dependent on TRAF-Binding Sequence. Viruses, 15, 2023
8T5N	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound) 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-06-14 公開日 2023-06-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound) To be published
8T5M	SOS2 crystal structure with fragment bound (compound 14) 分子名称: 1,2-ETHANEDIOL, 4-[(1R,2S)-1-hydroxy-2-{[2-(4-hydroxyphenyl)ethyl]amino}propyl]phenol, SULFATE ION, ... 著者 Gunn, R.J, Lawson, J.D, Ivetac, A, Ulaganathan, T, Coulombe, R, Fethiere, J. 登録日 2023-06-14 公開日 2024-01-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. J.Med.Chem., 67, 2024
8T5L	Crystal structure of STING CTD in complex with 2'3'-cGAMP 分子名称: Stimulator of interferon genes protein, cGAMP 著者 Li, Y, Li, P, Sun, D. 登録日 2023-06-13 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
8T5K	Crystal structure of STING CTD in complex with BDW-OH 分子名称: Stimulator of interferon genes protein, {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid 著者 Li, Y, Li, P, Sun, D. 登録日 2023-06-13 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
8T5J	Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Francisella philomiragia 分子名称: CHLORIDE ION, HEXANE-1,6-DIOL, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-06-13 公開日 2023-06-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of outer membrane lipoprotein carrier protein (LolA) from Francisella philomiragia To be published
8T5I	Crystal structure of human WDR5 in complex with MR4397 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, N-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamide, ... 著者 Kimani, S, Dong, A, Li, F, Loppnau, P, Ackloo, S, Vedadi, M, Brown, P.J, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) 登録日 2023-06-13 公開日 2023-08-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human WDR5 in complex with MR4397 To be published

<150151152153154155156157158159160161162163164165>