8T69

Human VMAT2 in complex with tetrabenazine

Summary for 8T69

Entry DOI	10.2210/pdb8t69/pdb
EMDB information	41066
Descriptor	Synaptic vesicular amine transporter, tetrabenazine (2 entities in total)
Functional Keywords	membrane protein, transporter
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	53936.29
Authors	Pidathala, S.,Dai, Y.,Lee, C.H. (deposition date: 2023-06-15, release date: 2023-11-01, Last modification date: 2023-12-13)
Primary citation	Pidathala, S.,Liao, S.,Dai, Y.,Li, X.,Long, C.,Chang, C.L.,Zhang, Z.,Lee, C.H. Mechanisms of neurotransmitter transport and drug inhibition in human VMAT2. Nature, 623:1086-1092, 2023 Cited by PubMed: 37914936 DOI: 10.1038/s41586-023-06727-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.89 Å)

Structure validation