1IAI
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![BU of 1iai by Molmil](/molmil-images/mine/1iai) | IDIOTYPE-ANTI-IDIOTYPE FAB COMPLEX | 分子名称: | ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A), IDIOTYPIC FAB 730.1.4 (IGG1) OF VIRUS NEUTRALIZING ANTIBODY | 著者 | Ban, N, Escobar, C, Garcia, R, Hasel, K, Day, J, Greenwood, A, McPherson, A. | 登録日 | 1993-12-28 | 公開日 | 1996-03-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of an idiotype-anti-idiotype Fab complex. Proc.Natl.Acad.Sci.USA, 91, 1994
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7F9W
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![BU of 7f9w by Molmil](/molmil-images/mine/7f9w) | CD25 in complex with Fab | 分子名称: | Heavy chain of Fab, Interleukin-2 receptor subunit alpha, Light chain of Fab | 著者 | Liu, C. | 登録日 | 2021-07-05 | 公開日 | 2022-01-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11, 2021
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6N5B
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![BU of 6n5b by Molmil](/molmil-images/mine/6n5b) | Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, Hemagglutinin, antibody heavy chain, ... | 著者 | Bajic, G, Maron, M.J, Schmidt, A.G. | 登録日 | 2018-11-21 | 公開日 | 2019-06-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope. Cell Host Microbe, 25, 2019
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5KVL
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![BU of 5kvl by Molmil](/molmil-images/mine/5kvl) | Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4 | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Huxford, T, King, A, Fleming, J.K, Wojciak, J.M. | 登録日 | 2016-07-14 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4 To Be Published
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6VY2
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![BU of 6vy2 by Molmil](/molmil-images/mine/6vy2) | |
4OQT
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![BU of 4oqt by Molmil](/molmil-images/mine/4oqt) | LINGO-1/Li81 Fab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Li81 Fab, ... | 著者 | Pepinsky, R.B, Arndt, J.W, Quan, C, Gao, Y, Quintero-Monzon, O, Lee, X, Mi, S. | 登録日 | 2014-02-10 | 公開日 | 2014-05-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | 主引用文献 | Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy. J.Pharmacol.Exp.Ther., 350, 2014
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6ZFO
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![BU of 6zfo by Molmil](/molmil-images/mine/6zfo) | Association of two complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-17 | 公開日 | 2020-07-08 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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6QKD
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![BU of 6qkd by Molmil](/molmil-images/mine/6qkd) | CRYSTAL STRUCTURE OF vhh-based FAB-fragment of antibody BCD-085 | 分子名称: | CHLORIDE ION, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | 著者 | Kostareva, O.S, Kolyadenko, I.A, Ulitin, A.B, Ekimova, V.M, Evdokimov, S.R, Garber, M.B, Tishchenko, T.V, Gabdulkhakov, A.G. | 登録日 | 2019-01-29 | 公開日 | 2019-07-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fab Fragment of VHH-Based Antibody Netakimab: Crystal Structure and Modeling Interaction with Cytokine IL-17A Crystals, 2019
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4NUY
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![BU of 4nuy by Molmil](/molmil-images/mine/4nuy) | Crystal structure of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes | 分子名称: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2 | 著者 | Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J. | 登録日 | 2013-12-04 | 公開日 | 2014-04-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.609 Å) | 主引用文献 | Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc.Natl.Acad.Sci.USA, 111, 2014
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3G6J
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![BU of 3g6j by Molmil](/molmil-images/mine/3g6j) | C3b in complex with a C3b specific Fab | 分子名称: | CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ... | 著者 | Wiesmann, C. | 登録日 | 2009-02-06 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement J.Biol.Chem., 284, 2009
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8CIN
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![BU of 8cin by Molmil](/molmil-images/mine/8cin) | BA.4/5-5 FAB IN COMPLEX WITH SARS-COV-2 BA.4 SPIKE GLYCOPROTEIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-5 fab HEAVY CHAIN, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E. | 登録日 | 2023-02-10 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
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4LEX
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6ZDG
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![BU of 6zdg by Molmil](/molmil-images/mine/6zdg) | Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-14 | 公開日 | 2020-07-29 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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4NUZ
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![BU of 4nuz by Molmil](/molmil-images/mine/4nuz) | Crystal structure of a glycosynthase mutant (D233Q) of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes | 分子名称: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2 | 著者 | Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J. | 登録日 | 2013-12-04 | 公開日 | 2014-04-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | 主引用文献 | Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies. Proc.Natl.Acad.Sci.USA, 111, 2014
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6MVL
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3KYK
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![BU of 3kyk by Molmil](/molmil-images/mine/3kyk) | Crystal structure of li33 Igg1 Fab | 分子名称: | Heavy Chain Li33 IgG1, Light Chain Li33 IgG1, SULFATE ION | 著者 | Silvian, L.F, Pepinsky, R.B, Walus, L. | 登録日 | 2009-12-06 | 公開日 | 2010-03-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis. Protein Sci., 19, 2010
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3FCT
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![BU of 3fct by Molmil](/molmil-images/mine/3fct) | MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN | 分子名称: | CADMIUM ION, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Romesberg, F.E, Santarsiero, B.D, Barnes, D, Yin, J, Spiller, B, Schultz, P.G, Stevens, R.C. | 登録日 | 1999-06-13 | 公開日 | 1999-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and kinetic evidence for strain in biological catalysis. Biochemistry, 37, 1998
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3WJL
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![BU of 3wjl by Molmil](/molmil-images/mine/3wjl) | Crystal structure of IIb selective Fc variant, Fc(V12), in complex with FcgRIIb | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-c, ... | 著者 | Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K. | 登録日 | 2013-10-11 | 公開日 | 2013-11-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131. Protein Eng.Des.Sel., 26, 2013
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4QNP
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![BU of 4qnp by Molmil](/molmil-images/mine/4qnp) | Crystal structure of the 2009 pandemic H1N1 influenza virus neuraminidase with a neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wan, H.Q, Yang, H, Shore, D.A, Garten, R.J, Couzens, L, Gao, J, Jiang, L.L, Carney, P.J, Villanueva, J, Stevens, J, Eichelberger, M.C. | 登録日 | 2014-06-18 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers. Nat Commun, 6, 2015
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3J7E
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![BU of 3j7e by Molmil](/molmil-images/mine/3j7e) | Electron cryo-microscopy of human papillomavirus 16 and H16.V5 Fab fragments | 分子名称: | H16.V5 Fab heavy chain, H16.V5 Fab light chain | 著者 | Lee, H, Brendle, S.A, Bywaters, S.M, Christensen, N.D, Hafenstein, S. | 登録日 | 2014-06-23 | 公開日 | 2014-11-26 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (13.6 Å) | 主引用文献 | A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment. J.Virol., 89, 2015
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3WJJ
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![BU of 3wjj by Molmil](/molmil-images/mine/3wjj) | Crystal structure of IIb selective Fc variant, Fc(P238D), in complex with FcgRIIb | 分子名称: | Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-b, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K. | 登録日 | 2013-10-10 | 公開日 | 2013-11-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131. Protein Eng.Des.Sel., 26, 2013
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8J1V
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8J1T
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5DYO
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![BU of 5dyo by Molmil](/molmil-images/mine/5dyo) | Fab43.1 complex with flourescein | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, Fab 43.1 Heavy Chain, Fab 43.1 Light Chain, ... | 著者 | Longenecker, K.L, Judge, R.A. | 登録日 | 2015-09-25 | 公開日 | 2016-01-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Three-dimensional structure, binding, and spectroscopic characteristics of the monoclonal antibody 43.1 directed to the carboxyphenyl moiety of fluorescein. Biopolymers, 105, 2016
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4I3R
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![BU of 4i3r by Molmil](/molmil-images/mine/4i3r) | Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ... | 著者 | Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D. | 登録日 | 2012-11-26 | 公開日 | 2013-01-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04. J.Virol., 87, 2013
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