7F9W

CD25 in complex with Fab

Summary for 7F9W

• Entry DOI: 10.2210/pdb7f9w/pdb
• EMDB information: 31499
• Descriptor: Interleukin-2 receptor subunit alpha, Light chain of Fab, Heavy chain of Fab (3 entities in total)
• Functional Keywords: cd25, antibody, il-2, antitumor protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 92184.34

Authors

Liu, C. (deposition date: 2021-07-05, release date: 2022-01-12)

• Primary citation: Song, D.,Liu, X.,Dong, C.,Wang, Q.,Sha, C.,Liu, C.,Ning, Z.,Han, J.,Liu, H.,Zong, M.,Zhao, Y.,Li, Y.,Liu, G.,Shao, X.,Dou, C.; Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity.; Sci Rep, 11:22966-22966, 2021; PubMed: 34824364; DOI: 10.1038/s41598-021-02449-y

Experimental method

ELECTRON MICROSCOPY (3.2 Å)