Association of two complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab

Summary for 6ZFO

Related6ZCZ 6ZHD 6ZDG 6ZER
EMDB information11184
DescriptorSpike glycoprotein, EY6A heavy chain, EY6A light chain, ... (4 entities in total)
Functional Keywordsey6a, rbd, spike glycoprotein, sars-cov-2, human neutralizing antibody, viral protein, immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains6
Total molecular weight139319.43
Duyvesteyn, H.M.E.,Zhou, D.,Zhao, Y.,Fry, E.E.,Ren, J.,Stuart, D.I. (deposition date: 2020-06-17, release date: 2020-07-08, Last modification date: 2020-08-12)
Primary citation
Zhou, D.,Duyvesteyn, H.M.E.,Chen, C.P.,Huang, C.G.,Chen, T.H.,Shih, S.R.,Lin, Y.C.,Cheng, C.Y.,Cheng, S.H.,Huang, Y.C.,Lin, T.Y.,Ma, C.,Huo, J.,Carrique, L.,Malinauskas, T.,Ruza, R.R.,Shah, P.N.M.,Tan, T.K.,Rijal, P.,Donat, R.F.,Godwin, K.,Buttigieg, K.R.,Tree, J.A.,Radecke, J.,Paterson, N.G.,Supasa, P.,Mongkolsapaya, J.,Screaton, G.R.,Carroll, M.W.,Gilbert-Jaramillo, J.,Knight, M.L.,James, W.,Owens, R.J.,Naismith, J.H.,Townsend, A.R.,Fry, E.E.,Zhao, Y.,Ren, J.,Stuart, D.I.,Huang, K.A.
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 2020
PubMed: 32737466 (PDB entries with the same primary citation)
DOI: 10.1038/s41594-020-0480-y
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers30 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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PDB entries from 2020-08-12