Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody.

Summary for 6ZCZ

DescriptorSpike glycoprotein, Nanobody, EY6A heavy chain, ... (7 entities in total)
Functional Keywordsey6a, rbd, spike glycoprotein, sars-cov-2, human neutralizing antibody, viral protein, immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains4
Total molecular weight87950.27
Zhou, D.,Zhao, Y.,Fry, E.E.,Ren, J.,Stuart, D.I. (deposition date: 2020-06-12, release date: 2020-06-24)
Primary citation
Zhou, D.,Duyvesteyn, H.M.E.,Chen, C.,Huang, C.,Chen, T.,Shih, S.,Lin, Y.,Cheng, C.,Cheng, S.,Huang, Y.,Lin, T.,Ma, C.,Huo, J.,Carrique, L.,Malinauskas, T.,Ruza, R.R.,Shah, P.N.M.,Tan, T.K.,Rijal, P.,Godwin, K.,Bewley, K.,Tree, J.,Radecke, J.,Paterson, N.G.,Supasa, P.,Mongkolsapaya, J.,Screaton, G.R.,Carroll, M.,James, W.,Owens, R.J.,Naismith, J.,Townsend, A.,Fry, E.E.,Zhao, Y.,Ren, J.,Stuart, D.I.,Huang, K.A.
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26050 1.1% 6.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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