6ZCZ
Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Spike protein S1 | polymer | 205 | 23150.9 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (F) | Nanobody | polymer | 151 | 16714.5 | 1 | Lama glama (llama) | ||
| 3 | C (H) | EY6A heavy chain | polymer | 226 | 24346.3 | 1 | Homo sapiens (human) | ||
| 4 | D (L) | EY6A light chain | polymer | 215 | 23315.9 | 1 | Homo sapiens (human) | ||
| 5 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | F, G, H, I, J (E, F, H, L) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 7 | K (L) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
E: 333 - 526 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 324 | - | expression tag |
| Thr 325 | - | expression tag |
| Gly 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| Lys 527 | - | expression tag |
| Lys 528 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87527.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 422.8 | |
| All* | Total formula weight | 87950.3 |
