Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab

Summary for 6ZER

Related6ZCZ 6ZDH 6ZDG
DescriptorRBD, heavy chain, light chain, ... (5 entities in total)
Functional Keywordsey6a, rbd, spike glycoprotein, sars-cov-2, human neutralizing antibody, viral protein/immune system, viral protein-immune system complex
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains9
Total molecular weight212305.45
Zhou, D.,Zhao, Y.,Fry, E.E.,Ren, J.,Stuart, D.I. (deposition date: 2020-06-16, release date: 2020-06-24)
Primary citation
Zhou, D.,Duyvesteyn, H.M.E.,Chen, C.,Huang, C.,Chen, T.,Shih, S.,Lin, Y.,Cheng, C.,Cheng, S.,Huang, Y.,Lin, T.,Ma, C.,Huo, J.,Carrique, L.,Malinauskas, T.,Ruza, R.R.,Shah, P.N.M.,Tan, T.K.,Rijal, P.,Godwin, K.,Bewley, K.,Tree, J.,Radecke, J.,Paterson, N.G.,Supasa, P.,Mongkolsapaya, J.,Screaton, G.R.,Carroll, M.,James, W.,Owens, R.J.,Naismith, J.,Townsend, A.,Fry, E.E.,Zhao, Y.,Ren, J.,Stuart, D.I.,Huang, K.A.
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2498 0.1% 0.5% 12.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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