3J7E
Electron cryo-microscopy of human papillomavirus 16 and H16.V5 Fab fragments
Summary for 3J7E
Entry DOI | 10.2210/pdb3j7e/pdb |
Related | 3J7G |
EMDB information | 5991 5992 5993 5994 |
Descriptor | H16.V5 Fab light chain, H16.V5 Fab heavy chain (2 entities in total) |
Functional Keywords | hpv16.v5 fab variable domain, hi and fg loops, hpv16 capsid, virus-fab complex, neutralization antibody, maturation, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 104484.52 |
Authors | Lee, H.,Brendle, S.A.,Bywaters, S.M.,Christensen, N.D.,Hafenstein, S. (deposition date: 2014-06-23, release date: 2014-11-26, Last modification date: 2018-07-18) |
Primary citation | Lee, H.,Brendle, S.A.,Bywaters, S.M.,Guan, J.,Ashley, R.E.,Yoder, J.D.,Makhov, A.M.,Conway, J.F.,Christensen, N.D.,Hafenstein, S. A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment. J.Virol., 89:1428-1438, 2015 Cited by PubMed: 25392224DOI: 10.1128/JVI.02898-14 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (13.6 Å) |
Structure validation
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