8CIN

BA.4/5-5 FAB IN COMPLEX WITH SARS-COV-2 BA.4 SPIKE GLYCOPROTEIN

Summary for 8CIN

• Entry DOI: 10.2210/pdb8cin/pdb
• Related: 8CBD 8CBE 8CBF
• EMDB information: 16680
• Descriptor: Spike glycoprotein, BA.4/5-5 fab HEAVY CHAIN, BA.4/5-5 fab LIGHT CHAIN, ... (5 entities in total)
• Functional Keywords: sars-cov2, spike, glycoprotein, coronavirus, antibody, fab, ba.4, ba.5, ba.4/5-5, cross-protective, omicron variant, vaccine, therapeutic, complex, neutralising, convalescent sera, viral protein, immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 9
• Total formula weight: 523600.00

Authors

Duyvesteyn, H.M.E.,Ren, J.,Stuart, D.I.,Fry, E.E. (deposition date: 2023-02-10, release date: 2024-02-21, Last modification date: 2024-04-10)

• Primary citation: Zhou, D.,Supasa, P.,Liu, C.,Dijokaite-Guraliuc, A.,Duyvesteyn, H.M.E.,Selvaraj, M.,Mentzer, A.J.,Das, R.,Dejnirattisai, W.,Temperton, N.,Klenerman, P.,Dunachie, S.J.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.; Nat Commun, 15:2734-2734, 2024; PubMed: 38548763; DOI: 10.1038/s41467-024-46982-6

Experimental method

ELECTRON MICROSCOPY (2.7 Å)