4LEX

Unliganded crystal structure of mAb7

Summary for 4LEX

• Entry DOI: 10.2210/pdb4lex/pdb
• Related: 4LF3
• Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN (3 entities in total)
• Functional Keywords: fab fragment, anti-gcgr, fab heavy and light chain, antibody, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 46632.94

Authors

Murray, J.M.,Mukund, S. (deposition date: 2013-06-26, release date: 2013-11-13, Last modification date: 2023-09-20)

• Primary citation: Mukund, S.,Shang, Y.,Clarke, H.J.,Madjidi, A.,Corn, J.E.,Kates, L.,Kolumam, G.,Chiang, V.,Luis, E.,Murray, J.,Zhang, Y.,Hotzel, I.,Koth, C.M.,Allan, B.B.; Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.; J.Biol.Chem., 288:36168-36178, 2013; PubMed: 24189067; DOI: 10.1074/jbc.M113.496984

Experimental method

X-RAY DIFFRACTION (2.02 Å)