4LF3
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
Summary for 4LF3
Entry DOI | 10.2210/pdb4lf3/pdb |
Related | 4ERS 4LEX |
Descriptor | Fab heavy chain, Fab light chain, Glucagon receptor, ... (4 entities in total) |
Functional Keywords | fab fragment, gcgr, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P47871 |
Total number of polymer chains | 6 |
Total formula weight | 119231.48 |
Authors | Murray, J.M.,Mukund, S. (deposition date: 2013-06-26, release date: 2013-11-13, Last modification date: 2023-09-20) |
Primary citation | Mukund, S.,Shang, Y.,Clarke, H.J.,Madjidi, A.,Corn, J.E.,Kates, L.,Kolumam, G.,Chiang, V.,Luis, E.,Murray, J.,Zhang, Y.,Hotzel, I.,Koth, C.M.,Allan, B.B. Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor. J.Biol.Chem., 288:36168-36178, 2013 Cited by PubMed: 24189067DOI: 10.1074/jbc.M113.496984 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.735 Å) |
Structure validation
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