4LF3
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004930 | molecular_function | G protein-coupled receptor activity |
| C | 0004967 | molecular_function | glucagon receptor activity |
| C | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| C | 0016020 | cellular_component | membrane |
| F | 0004930 | molecular_function | G protein-coupled receptor activity |
| F | 0004967 | molecular_function | glucagon receptor activity |
| F | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| F | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| A | TYR192-HIS198 | |
| B | TYR423-HIS429 |
| site_id | PS00649 |
| Number of Residues | 25 |
| Details | G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDkys.CWpdTpanttanisCP |
| Chain | Residue | Details |
| C | CYS58-PRO82 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"28514451","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22908259","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28514451","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ERS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
