4LF3
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Fab heavy chain | polymer | 214 | 23263.8 | 2 | Mus musculus (mouse) | ||
| 2 | B, E (B, E) | Fab light chain | polymer | 231 | 25001.0 | 2 | Mus musculus (mouse) | ||
| 3 | C, F (C, F) | Glucagon receptor | polymer | 95 | 11350.9 | 2 | UniProt (P47871) Pfam (PF02793) | Homo sapiens (human) | GL-R |
| 4 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
C, F: 29 - 123 (UniProt: P47871)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Gly 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 119231.5 | |
| All* | Total formula weight | 119231.5 |
