4LF3
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Fab heavy chain | polymer | 214 | 23263.8 | 2 | Mus musculus (mouse) | ||
2 | B, E | Fab light chain | polymer | 231 | 25001.0 | 2 | Mus musculus (mouse) | ||
3 | C, F | Glucagon receptor | polymer | 95 | 11350.9 | 2 | UniProt (P47871) Pfam (PF02793) In PDB | Homo sapiens (human) | GL-R |
4 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
C, F: 29 - 123 (UniProt: P47871)
PDB | External Database | Details |
---|---|---|
Ser 40 | Gly 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 119231.5 | |
All* | Total formula weight | 119231.5 |