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2F8O
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A Native to Amyloidogenic Transition Regulated by a Backbone Trigger
分子名称: Beta-2-microglobulin
著者Eakin, C.M, Berman, A.J, Miranker, A.D.
登録日2005-12-02
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A native to amyloidogenic transition regulated by a backbone trigger.
Nat.Struct.Mol.Biol., 13, 2006
2F8P
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Crystal structure of obelin following Ca2+ triggered bioluminescence suggests neutral coelenteramide as the primary excited state
分子名称: CALCIUM ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, Obelin
著者Liu, Z.J, Stepanyuk, G.A, Vysotski, E.S, Lee, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-12-03
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of obelin after Ca2+-triggered bioluminescence suggests neutral coelenteramide as the primary excited state.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2F8Q
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An alkali thermostable F/10 xylanase from alkalophilic Bacillus sp. NG-27
分子名称: MAGNESIUM ION, alkaline thermostable endoxylanase
著者Ramakumar, S, Manikandan, K, Bhardwaj, A, Ghosh, A, Reddy, V.S.
登録日2005-12-03
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of native and xylosaccharide-bound alkali thermostable xylanase from an alkalophilic Bacillus sp. NG-27: structural insights into alkalophilicity and implications for adaptation to polyextreme conditions.
Protein Sci., 15, 2006
2F8S
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Crystal structure of Aa-Ago with externally-bound siRNA
分子名称: 5'-R(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*AP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3', Argonaute protein
著者Yuan, Y.R, Chen, H.Y, Patel, D.J.
登録日2005-12-03
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA.
Structure, 14, 2006
2F8T
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Crystal structure of Aa-Ago with externally-bound siRNA
分子名称: 26-MER, Argonaute protein
著者Yuan, Y.R, Chen, H.Y, Patel, D.J.
登録日2005-12-03
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA.
Structure, 14, 2006
2F8U
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G-quadruplex structure formed in human Bcl-2 promoter, hybrid form
分子名称: 5'-D(*GP*GP*GP*CP*GP*CP*GP*GP*GP*AP*GP*GP*AP*AP*TP*TP*GP*GP*GP*CP*GP*GP*G)-3'
著者Dai, J, Chen, D, Carver, M, Yang, D.
登録日2005-12-03
公開日2006-11-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.
Nucleic Acids Res., 34, 2006
2F8V
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Structure of full length telethonin in complex with the N-terminus of titin
分子名称: N2B-Titin Isoform, SULFATE ION, Telethonin
著者Pinotsis, N, Petoukhov, M, Lange, S, Svergun, D, Zou, P, Gautel, M, Wilmanns, M.
登録日2005-12-04
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus.
J.Struct.Biol., 155, 2006
2F8W
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Crystal structure of d(CACGTG)2
分子名称: 1,3-DIAMINOPROPANE, 5'-D(*CP*AP*CP*GP*TP*G)-3', SPERMINE
著者Narayana, N, Shamala, N, Ganesh, K.N, Viswamitra, M.A.
登録日2005-12-04
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Interaction between the Z-Type DNA Duplex and 1,3-Propanediamine: Crystal Structure of d(CACGTG)2 at 1.2 A Resolution
Biochemistry, 45, 2006
2F8X
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Crystal structure of activated Notch, CSL and MAML on HES-1 promoter DNA sequence
分子名称: 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ...
著者Nam, Y, Sliz, P, Blacklow, S.C.
登録日2005-12-04
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Cell(Cambridge,Mass.), 124, 2006
2F8Y
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Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution.
分子名称: Notch homolog 1, translocation-associated (Drosophila), SULFATE ION
著者Nam, Y, Sliz, P, Blacklow, S.C.
登録日2005-12-04
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Cell(Cambridge,Mass.), 124, 2006
2F8Z
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Crystal structure of human FPPS in complex with zoledronate and isopentenyl diphosphate
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl Diphosphate Synthase, MAGNESIUM ION, ...
著者Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W.
登録日2005-12-02
公開日2006-02-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
2F90
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Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4-
分子名称: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION
著者Wang, Y, Liu, L, Wei, Z, Gong, W.
登録日2005-12-05
公開日2006-10-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase
J.Biol.Chem., 281, 2006
2F91
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1.2A resolution structure of a crayfish trypsin complexed with a peptide inhibitor, SGTI
分子名称: CADMIUM ION, CHLORIDE ION, Serine protease inhibitor I/II, ...
著者Fodor, K, Harmat, V, Hetenyi, C, Kardos, J, Antal, J, Perczel, A, Patthy, A, Katona, G, Graf, L.
登録日2005-12-05
公開日2006-04-18
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis.
Biochemistry, 45, 2006
2F92
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Crystal structure of human FPPS in complex with alendronate
分子名称: 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, Farnesyl Diphosphate Synthase, PHOSPHATE ION, ...
著者Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W.
登録日2005-12-05
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
2F93
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K Intermediate Structure of Sensory Rhodopsin II/Transducer Complex in Combination with the Ground State Structure
分子名称: RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ...
著者Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I.
登録日2005-12-05
公開日2006-03-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
2F94
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Crystal structure of human FPPS in complex with ibandronate
分子名称: Farnesyl Diphosphate Synthase, IBANDRONATE, PHOSPHATE ION, ...
著者Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W.
登録日2005-12-05
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
Chemmedchem, 1, 2006
2F95
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M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
分子名称: RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ...
著者Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I.
登録日2005-12-05
公開日2006-03-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
2F96
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2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T)
分子名称: MAGNESIUM ION, Ribonuclease T
著者Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2005-12-05
公開日2006-02-14
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover.
Structure, 15, 2007
2F97
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Effector Binding Domain of BenM (crystals generated from high pH conditions)
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, HTH-type transcriptional regulator benM, ...
著者Ezezika, O.C, Haddad, S, Neidle, E.L, Momany, C.
登録日2005-12-05
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Oligomerization of BenM, a LysR-type transcriptional regulator: structural basis for the aggregation of proteins in this family.
Acta Crystallogr.,Sect.F, 63, 2007
2F98
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Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
分子名称: Aklanonic Acid methyl Ester Cyclase, AknH, METHYL 5,7-DIHYDROXY-2-METHYL-4,6,11-TRIOXO-3,4,6,11-TETRAHYDROTETRACENE-1-CARBOXYLATE, ...
著者Kallio, P, Sultana, A, Neimi, J, Mantsala, P, Schneider, G.
登録日2005-12-05
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
J.Mol.Biol., 357, 2006
2F99
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Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
分子名称: Aklanonic Acid methyl Ester Cyclase, AknH, SULFATE ION, ...
著者Kallio, P, Sultana, A, Neimi, J, Mantsala, P, Schneider, G.
登録日2005-12-05
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
J.Mol.Biol., 357, 2006
2F9A
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HMG-CoA synthase from Brassica juncea in complex with F-244
分子名称: (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid, 3-Hydroxy-3-methylglutaryl coenzyme A synthase 1
著者Pojer, F, Ferrer, J.L, Richard, S.B, Noel, J.P.
登録日2005-12-05
公開日2006-07-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2F9B
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Discovery of Novel Heterocyclic Factor VIIa Inhibitors
分子名称: Coagulation factor VII, Tissue factor, {5-(5-AMINO-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)-6-HYDROXY-3'-NITRO-BIPHENYL-3-YL]-ACETIC ACID
著者Rai, R, Kolesnikov, A, Sprengeler, P.A, Torkelson, S, Ton, T, Katz, B.A, Yu, C, Hendrix, J, Shrader, W.D, Stephens, R, Cabuslay, R, Sanford, E, Young, W.B.
登録日2005-12-05
公開日2006-02-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Discovery of novel heterocyclic factor VIIa inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2F9C
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Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6
分子名称: CESIUM ION, Hypothetical protein YDCK
著者Benach, J, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, H, Cooper, B, Acton, X.T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2005-12-05
公開日2005-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of YDCK from Salmonella cholerae NESG target SCR6.
To be Published
2F9D
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2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155
分子名称: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
著者Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M.
登録日2005-12-05
公開日2006-01-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006

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