2F8Y
Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution.
Summary for 2F8Y
| Entry DOI | 10.2210/pdb2f8y/pdb |
| Descriptor | Notch homolog 1, translocation-associated (Drosophila), SULFATE ION (3 entities in total) |
| Functional Keywords | notch, ankyrin repeats, transcription |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity). Notch 1 intracellular domain: Nucleus (By similarity): P46531 |
| Total number of polymer chains | 2 |
| Total formula weight | 49196.82 |
| Authors | Nam, Y.,Sliz, P.,Blacklow, S.C. (deposition date: 2005-12-04, release date: 2006-04-04, Last modification date: 2023-08-30) |
| Primary citation | Nam, Y.,Sliz, P.,Song, L.,Aster, J.C.,Blacklow, S.C. Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell(Cambridge,Mass.), 124:973-983, 2006 Cited by PubMed: 16530044DOI: 10.1016/j.cell.2005.12.037 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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