2F9A

HMG-CoA synthase from Brassica juncea in complex with F-244

Summary for 2F9A

Entry DOI	10.2210/pdb2f9a/pdb
Related	2F82 2FA0 2FA3
Descriptor	3-Hydroxy-3-methylglutaryl coenzyme A synthase 1, (7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid (3 entities in total)
Functional Keywords	hmgs1, f-244, transferase
Biological source	Brassica juncea
Total number of polymer chains	1
Total formula weight	50352.26
Authors	Pojer, F.,Ferrer, J.L.,Richard, S.B.,Noel, J.P. (deposition date: 2005-12-05, release date: 2006-07-25, Last modification date: 2023-08-30)
Primary citation	Pojer, F.,Ferrer, J.L.,Richard, S.B.,Nagegowda, D.A.,Chye, M.L.,Bach, T.J.,Noel, J.P. Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases. Proc.Natl.Acad.Sci.Usa, 103:11491-11496, 2006 Cited by PubMed: 16864776 DOI: 10.1073/pnas.0604935103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.51 Å)

Structure validation