2F8S
Crystal structure of Aa-Ago with externally-bound siRNA
Summary for 2F8S
Entry DOI | 10.2210/pdb2f8s/pdb |
Related | 2F8T |
Descriptor | 5'-R(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*AP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3', Argonaute protein (3 entities in total) |
Functional Keywords | argonaute, sirna, risc loading complex, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 4 |
Total formula weight | 180491.04 |
Authors | Yuan, Y.R.,Chen, H.Y.,Patel, D.J. (deposition date: 2005-12-03, release date: 2006-10-31, Last modification date: 2023-08-30) |
Primary citation | Yuan, Y.R.,Pei, Y.,Chen, H.Y.,Tuschl, T.,Patel, D.J. A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA. Structure, 14:1557-1565, 2006 Cited by PubMed: 17027504DOI: 10.1016/j.str.2006.08.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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