7STK
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7STH
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7TYJ
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![BU of 7tyj by Molmil](/molmil-images/mine/7tyj) | Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was focused on one of two halves with C1 symmetry applied | 分子名称: | Insulin receptor-related protein | 著者 | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | 登録日 | 2022-02-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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7TYK
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![BU of 7tyk by Molmil](/molmil-images/mine/7tyk) | Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was applied with C2 symmetry | 分子名称: | Insulin receptor-related protein | 著者 | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | 登録日 | 2022-02-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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7TYM
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![BU of 7tym by Molmil](/molmil-images/mine/7tym) | Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry | 分子名称: | Insulin receptor-related protein | 著者 | Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C. | 登録日 | 2022-02-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor. Nat.Struct.Mol.Biol., 30, 2023
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2IBG
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3L5H
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![BU of 3l5h by Molmil](/molmil-images/mine/3l5h) | Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, SULFATE ION, ... | 著者 | Xu, Y, Garrett, T.P.J, Zhang, J.G. | 登録日 | 2009-12-21 | 公開日 | 2010-05-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285, 2010
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7U7N
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![BU of 7u7n by Molmil](/molmil-images/mine/7u7n) | IL-27 quaternary receptor signaling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | 著者 | Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. | 登録日 | 2022-03-07 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structure of the IL-27 quaternary receptor signaling complex. Elife, 11, 2022
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7U6E
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7U6D
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3MTR
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![BU of 3mtr by Molmil](/molmil-images/mine/3mtr) | Crystal structure of the Ig5-FN1 tandem of human NCAM | 分子名称: | Neural cell adhesion molecule 1, SULFATE ION | 著者 | Lavie, A, Foley, D.A. | 登録日 | 2010-04-30 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and mutagenesis of neural cell adhesion molecule domains: evidence for flexibility in the placement of polysialic acid attachment sites J.Biol.Chem., 285, 2010
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3MX0
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![BU of 3mx0 by Molmil](/molmil-images/mine/3mx0) | Crystal Structure of EphA2 ectodomain in complex with ephrin-A5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ... | 著者 | Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S. | 登録日 | 2010-05-06 | 公開日 | 2010-06-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | 主引用文献 | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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1TDQ
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![BU of 1tdq by Molmil](/molmil-images/mine/1tdq) | Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins | 分子名称: | Aggrecan core protein, CALCIUM ION, Tenascin-R | 著者 | Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T. | 登録日 | 2004-05-24 | 公開日 | 2004-08-31 | 最終更新日 | 2021-03-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins Structure, 12, 2004
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3N1G
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![BU of 3n1g by Molmil](/molmil-images/mine/3n1g) | Crystal structure of DhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Desert hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1Q
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![BU of 3n1q by Molmil](/molmil-images/mine/3n1q) | Crystal Structure of DhhN bound to CDOFn3 | 分子名称: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1F
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![BU of 3n1f by Molmil](/molmil-images/mine/3n1f) | Crystal Structure of IhhN bound to CDOFn3 | 分子名称: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1M
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![BU of 3n1m by Molmil](/molmil-images/mine/3n1m) | Crystal Structure of IhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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7Z0L
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![BU of 7z0l by Molmil](/molmil-images/mine/7z0l) | IL-27 signalling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | 著者 | Jin, Y, Gardner, S, Bubeck, D. | 登録日 | 2022-02-23 | 公開日 | 2022-07-27 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural insights into the assembly and activation of the IL-27 signaling complex. Embo Rep., 23, 2022
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7YQ3
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![BU of 7yq3 by Molmil](/molmil-images/mine/7yq3) | human insulin receptor bound with A43 DNA aptamer and insulin | 分子名称: | IR-A43 aptamer, Insulin A chain, Insulin, ... | 著者 | Kim, J, Yunn, N, Ryu, S, Cho, Y. | 登録日 | 2022-08-05 | 公開日 | 2022-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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7YQ4
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![BU of 7yq4 by Molmil](/molmil-images/mine/7yq4) | human insulin receptor bound with A62 DNA aptamer and insulin - locally refined | 分子名称: | IR-A62 aptamer, Insulin A chain, Insulin, ... | 著者 | Kim, J, Yunn, N, Ryu, S, Cho, Y. | 登録日 | 2022-08-05 | 公開日 | 2022-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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7YQ6
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![BU of 7yq6 by Molmil](/molmil-images/mine/7yq6) | human insulin receptor bound with A62 DNA aptamer | 分子名称: | IR-A62 aptamer, Isoform Short of Insulin receptor | 著者 | Kim, J, Yunn, N, Ryu, S, Cho, Y. | 登録日 | 2022-08-05 | 公開日 | 2022-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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7YQ5
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![BU of 7yq5 by Molmil](/molmil-images/mine/7yq5) | human insulin receptor bound with A62 DNA aptamer and insulin | 分子名称: | IR-A62 aptamer, Insulin A chain, Insulin, ... | 著者 | Kim, J, Yunn, N, Ryu, S, Cho, Y. | 登録日 | 2022-08-05 | 公開日 | 2022-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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3N1P
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![BU of 3n1p by Molmil](/molmil-images/mine/3n1p) | Crystal Structure of IhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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2JIX
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![BU of 2jix by Molmil](/molmil-images/mine/2jix) | Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor | 分子名称: | ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR | 著者 | Liu, Z, Stoll, V.S, DeVries, P, Jakob, C.G, Xie, N, Simmer, R.L, Lacy, S.E, Egan, D.A, Harlan, J.E, Lesniewski, R.R, Reilly, E.B. | 登録日 | 2007-07-02 | 公開日 | 2007-07-10 | 最終更新日 | 2020-03-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site. Blood, 110, 2007
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2JLL
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![BU of 2jll by Molmil](/molmil-images/mine/2jll) | Crystal structure of NCAM2 IgIV-FN3II | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Kulahin, N, Rasmussen, K, Kristensen, O, Kastrup, J, Berezin, V, Bock, E, Walmod, P, Gajhede, M. | 登録日 | 2008-09-10 | 公開日 | 2009-11-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule. Structure, 19, 2011
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