PDB: 395 件ウェブページステータス検索Chemie searchBIRD

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4BKA	crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 著者 Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. 登録日 2013-04-23 公開日 2013-07-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (5.3 Å) 主引用文献 Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
5J7C	A picomolar affinity FN3 domain in complex with hen egg-white lysozyme 分子名称: FNfn10-anti-lysozyme (DE0.4.1), Lysozyme C 著者 Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M. 登録日 2016-04-06 公開日 2016-08-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.535 Å) 主引用文献 Circumventing the stability-function trade-off in an engineered FN3 domain. Protein Eng.Des.Sel., 2016
5J12	Structure of human TSLP:TSLPR in complex with mouse IL-7Ralpha 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ... 著者 Verstraete, K, Savvides, S.N. 登録日 2016-03-28 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Structure of human TSLP:TSLPR in complex with mouse IL-7Ralpha To Be Published
5J11	Structure of human TSLP in complex with TSLPR and IL-7Ralpha 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ... 著者 Verstraete, K, Savvides, S.N. 登録日 2016-03-28 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma. Nat Commun, 8, 2017
2JIX	Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor 分子名称: ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR 著者 Liu, Z, Stoll, V.S, DeVries, P, Jakob, C.G, Xie, N, Simmer, R.L, Lacy, S.E, Egan, D.A, Harlan, J.E, Lesniewski, R.R, Reilly, E.B. 登録日 2007-07-02 公開日 2007-07-10 最終更新日 2020-03-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site. Blood, 110, 2007
2JLL	Crystal structure of NCAM2 IgIV-FN3II 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... 著者 Kulahin, N, Rasmussen, K, Kristensen, O, Kastrup, J, Berezin, V, Bock, E, Walmod, P, Gajhede, M. 登録日 2008-09-10 公開日 2009-11-17 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule. Structure, 19, 2011
1A22	HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR 分子名称: GROWTH HORMONE, GROWTH HORMONE RECEPTOR 著者 De Vos, A.M, Ultsch, M. 登録日 1998-01-15 公開日 1998-04-29 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J.Mol.Biol., 277, 1998
1CN4	ERYTHROPOIETIN COMPLEXED WITH EXTRACELLULAR DOMAINS OF ERYTHROPOIETIN RECEPTOR 分子名称: PROTEIN (ERYTHROPOIETIN RECEPTOR), PROTEIN (ERYTHROPOIETIN) 著者 Stroud, R.M, Reid, S.W. 登録日 1999-05-25 公開日 1999-08-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature, 395, 1998
8A1F	Human PTPRK N-terminal domains MAM-Ig-FN1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E. 登録日 2022-06-01 公開日 2023-03-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
8BXR	Titin FnIII-domain I109-I111 (I/A4-A/A6) from the MIR region 分子名称: 1,2-ETHANEDIOL, Titin 著者 Mayans, O, Fleming, J.R, Williams, R. 登録日 2022-12-09 公開日 2023-02-15 最終更新日 2023-03-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis. Biomedicines, 11, 2023
5C6P	protein C 分子名称: (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D 著者 Lu, M. 登録日 2015-06-23 公開日 2015-09-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
1TDQ	Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins 分子名称: Aggrecan core protein, CALCIUM ION, Tenascin-R 著者 Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T. 登録日 2004-05-24 公開日 2004-08-31 最終更新日 2021-03-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins Structure, 12, 2004
1AXI	STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE 分子名称: GROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION 著者 Atwell, S, Ultsch, M, De Vos, A.M, Wells, J.A. 登録日 1997-10-15 公開日 1998-01-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural plasticity in a remodeled protein-protein interface. Science, 278, 1997
1EER	CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS 分子名称: ERYTHROPOIETIN, ERYTHROPOIETIN RECEPTOR 著者 Syed, R.S, Li, C. 登録日 1998-07-24 公開日 1999-10-01 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature, 395, 1998
1EBA	COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN INACTIVE PEPTIDE [EMP33] CONTAINS 3,5-DIBROMOTYROSINE IN POSITION 4 (DENOTED DBY) 分子名称: PROTEIN (EPO MIMETICS PEPTIDE 33), PROTEIN (ERYTHROPOIETIN RECEPTOR) 著者 Livnah, O, Stura, E.A, Wilson, I.A. 登録日 1998-10-02 公開日 1998-11-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation. Nat.Struct.Biol., 5, 1998
2IBG	Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog 分子名称: CG9211-PA, PHOSPHATE ION, Protein hedgehog 著者 McLellan, J.S, Leahy, D.J. 登録日 2006-09-11 公開日 2006-10-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc.Natl.Acad.Sci.Usa, 103, 2006
1BQU	CYTOKYNE-BINDING REGION OF GP130 分子名称: GLYCEROL, PROTEIN (GP130), SULFATE ION 著者 Bravo, J, Staunton, D, Heath, J.K, Jones, E.Y. 登録日 1998-08-18 公開日 1998-08-26 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a cytokine-binding region of gp130. EMBO J., 17, 1998
1ERN	NATIVE STRUCTURE OF THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] 分子名称: PROTEIN (ERYTHROPOIETIN RECEPTOR) 著者 Livnah, O, Stura, E.A, Wilson, I.A. 登録日 1999-01-11 公開日 2000-01-07 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science, 283, 1999
1EBP	COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN AGONIST PEPTIDE [EMP1] 分子名称: EPO MIMETICS PEPTIDE 1, EPO RECEPTOR 著者 Livnah, O, Stura, E.A, Wilson, I.A. 登録日 1996-05-07 公開日 1997-07-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A. Science, 273, 1996
3L5H	Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, SULFATE ION, ... 著者 Xu, Y, Garrett, T.P.J, Zhang, J.G. 登録日 2009-12-21 公開日 2010-05-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285, 2010
7MQS	The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Isoform Short of Insulin receptor 著者 Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. 登録日 2021-05-06 公開日 2022-03-16 最終更新日 2023-03-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nat.Chem.Biol., 18, 2022
7NE1	Structure of the complex between Netrin-1 and its receptor Neogenin 分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. 登録日 2021-02-02 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
7NDG	Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ... 著者 Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. 登録日 2021-02-01 公開日 2021-03-31 最終更新日 2021-04-28 実験手法 ELECTRON MICROSCOPY (5.98 Å) 主引用文献 Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
7NE0	Structure of the ternary complex between Netrin-1, Repulsive-Guidance Molecule-B (RGMB) and Neogenin 分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. 登録日 2021-02-02 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
3NPZ	Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL) 分子名称: Prolactin, Prolactin receptor 著者 Van Agthoven, J, England, P, Goffin, V, Broutin, I. 登録日 2010-06-29 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone. J.Mol.Biol., 404, 2010

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