2IBG

Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog

Summary for 2IBG

• Entry DOI: 10.2210/pdb2ibg/pdb
• Related: 2IBB
• Descriptor: CG9211-PA, Protein hedgehog, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: ihog, hedgehog, fibronectin type iii, protein binding
• Biological source: Drosophila melanogaster (fruit fly); More
• Cellular location: Membrane; Single-pass type I membrane protein (Potential): Q9VM64; Nucleus. Protein hedgehog N-product: Cell membrane; Lipid-anchor; Extracellular side. Protein hedgehog C-product: Secreted, extracellular space: Q02936
• Total number of polymer chains: 8
• Total formula weight: 167386.77

Authors

McLellan, J.S.,Leahy, D.J. (deposition date: 2006-09-11, release date: 2006-10-24, Last modification date: 2023-08-30)

• Primary citation: McLellan, J.S.,Yao, S.,Zheng, X.,Geisbrecht, B.V.,Ghirlando, R.,Beachy, P.A.,Leahy, D.J.; Structure of a heparin-dependent complex of Hedgehog and Ihog.; Proc.Natl.Acad.Sci.Usa, 103:17208-17213, 2006; PubMed: 17077139; DOI: 10.1073/pnas.0606738103

Experimental method

X-RAY DIFFRACTION (2.2 Å)