3L5H

Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes

Summary for 3L5H

Entry DOI	10.2210/pdb3l5h/pdb
Related	3L5I 3L5J
Descriptor	Interleukin-6 receptor subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	ig-like, fniii, cell membrane, disulfide bond, glycoprotein, immunoglobulin domain, membrane, phosphoprotein, receptor, secreted, transmembrane, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	71026.32
Authors	Xu, Y.,Garrett, T.P.J.,Zhang, J.G. (deposition date: 2009-12-21, release date: 2010-05-19, Last modification date: 2020-07-29)
Primary citation	Xu, Y.,Kershaw, N.J.,Luo, C.S.,Soo, P.,Pocock, M.J.,Czabotar, P.E.,Hilton, D.J.,Nicola, N.A.,Garrett, T.P.,Zhang, J.G. Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285:21214-21218, 2010 Cited by PubMed: 20489211 DOI: 10.1074/jbc.C110.129502 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation