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3L5H

Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Interleukin-6 receptor subunit betapolymer58967013.71UniProt (P40189)
Pfam (PF06328)
Pfam (PF09240)
Pfam (PF00041)
Homo sapiens (human)IL-6R-beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, gp130, CDw130, Oncostatin-M receptor subunit alpha
2B, D, H
(B, D, H)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.43In PDB
GlyTouCan (G42666HT)
3C, F
(C, F)
beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.72In PDB
GlyTouCan (G53755TJ)
4E
(E)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
5G
(G)
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched367.31In PDB
GlyTouCan (G86851RC)
6I, J, K
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight67013.7
BranchedNumber of molecules7
Total formula weight3724.5
Non-Polymers*Number of molecules3
Total formula weight288.2
All*Total formula weight71026.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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