7YQ4
human insulin receptor bound with A62 DNA aptamer and insulin - locally refined
Summary for 7YQ4
Entry DOI | 10.2210/pdb7yq4/pdb |
EMDB information | 34019 |
Descriptor | Isoform Short of Insulin receptor, Insulin, isoform 2, Insulin A chain, ... (4 entities in total) |
Functional Keywords | receptor-ligand complex_b_local, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 221017.90 |
Authors | |
Primary citation | Kim, J.,Yunn, N.O.,Park, M.,Kim, J.,Park, S.,Kim, Y.,Noh, J.,Ryu, S.H.,Cho, Y. Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures Nat Commun, 13:6500-, 2022 Cited by DOI: 10.1038/s41467-022-34292-8PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.95 Å) |
Structure validation
Download full validation report