PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

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8EPM	Human R-type voltage-gated calcium channel Cav2.3 CH2II-deleted mutant at 3.1 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gao, S, Yao, X, Yan, N. 登録日 2022-10-06 公開日 2022-12-14 最終更新日 2023-07-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments. Nat Commun, 13, 2022
8B9I	Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9G	Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9L	Cryo-EM structure of MLE 分子名称: Dosage compensation regulator 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9K	Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7modUUC, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.04 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9J	Cryo-EM structure of MLE in complex with ADP:AlF4 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8EPU	1.6 A crystal structure of the lipocalin dog allergen Can f 1 with the C118S mutation 分子名称: Major allergen Can f 1 著者 Min, J, Pedersen, L.C, Geoffrey, M.A. 登録日 2022-10-06 公開日 2023-04-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7. Front Allergy, 4, 2023
8EPV	2.2 A crystal structure of the lipocalin cat allergen Fel d 7 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Fel d 7 allergen, ... 著者 Min, J, Pedersen, L.C, Geoffrey, M.A. 登録日 2022-10-06 公開日 2023-04-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7. Front Allergy, 4, 2023
8EPW	Crystal Structure of KRAS4b-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF 分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. 登録日 2022-10-06 公開日 2023-06-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D . Commun Biol, 6, 2023
8H2H	Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase 分子名称: Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3') 著者 Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M. 登録日 2022-10-06 公開日 2022-11-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Functionalized graphene grids with various charges for single-particle cryo-EM. Nat Commun, 13, 2022
8H2G	Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Park, J.H, Ishimoto, N, Park, S.Y. 登録日 2022-10-06 公開日 2023-10-11 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism To Be Published
8B9F	Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion 分子名称: Complement decay-accelerating factor, Genome polyprotein, SPHINGOSINE 著者 Stuart, D.I, Ren, J, Qin, L, Zhou, D. 登録日 2022-10-05 公開日 2022-12-07 最終更新日 2023-01-04 実験手法 ELECTRON MICROSCOPY (3.93 Å) 主引用文献 Switching of Receptor Binding Poses between Closely Related Enteroviruses. Viruses, 14, 2022
8EOP	Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Alam, A, Le, L.T.M, Thompson, J.R. 登録日 2022-10-04 公開日 2022-12-21 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms. Embo J., 42, 2023
8EP1	Eag Kv channel with voltage sensor in the down conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EOW	Eag Kv channel with voltage sensor in the up conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8EP0	Eag Kv channel with voltage sensor in the intermediate conformation 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Mandala, V.S, MacKinnon, R. 登録日 2022-10-04 公開日 2022-11-16 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022
8B8S	Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3 分子名称: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 著者 Kachariya, N, Sattler, M, Keil, P, Strasser, K. 登録日 2022-10-04 公開日 2022-11-09 最終更新日 2024-06-19 実験手法 SOLUTION NMR, SOLUTION SCATTERING 主引用文献 Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA. Nucleic Acids Res., 51, 2023
8B8R	Complex of Echovirus 11 with its attaching receptor decay-accelerating factor (CD55) 分子名称: DECAY ACCELERATING FACTOR (CD55), SPHINGOSINE, VP1, ... 著者 Stuart, D.I, Ren, J, Zhou, D, Qin, L. 登録日 2022-10-04 公開日 2022-12-07 最終更新日 2023-01-04 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Switching of Receptor Binding Poses between Closely Related Enteroviruses. Viruses, 14, 2022
8EOJ	Microsomal triglyceride transfer protein 分子名称: Microsomal triglyceride transfer protein large subunit, Protein disulfide-isomerase 著者 Zhang, Z. 登録日 2022-10-03 公開日 2023-05-03 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
8EOG	Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine 分子名称: (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. 登録日 2022-10-03 公開日 2023-05-24 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 EMC chaperone-Ca V structure reveals an ion channel assembly intermediate. Nature, 619, 2023
8EOH	crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid 分子名称: 12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Liu, J, Scott, E.E. 登録日 2022-10-03 公開日 2023-08-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281. J.Biol.Chem., 299, 2023
8H1O	Cryo-EM structure of KpFtsZ-monobody double helical tube 分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Mb(Ec/KpFtsZ_S1) 著者 Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H. 登録日 2022-10-03 公開日 2023-08-02 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody. Nat Commun, 14, 2023
8EOK	Structure of the C3bB proconvertase in complex with lufaxin and factor Xa 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activated factor Xa heavy chain, Complement C3 beta chain, ... 著者 Andersen, J.F, Lei, H. 登録日 2022-10-03 公開日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
8ENU	Structure of the C3bB proconvertase in complex with lufaxin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... 著者 Andersen, J.F, Lei, H. 登録日 2022-09-30 公開日 2023-08-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
8ENJ	Design, synthesis, biological evaluation, and X-ray crystallography of diarylpyrazole derivatives possessing terminal arylsulfonamide moieties as anti-proliferative agents targeting c-Jun N-terminal kinase (JNK) 分子名称: Mitogen-activated protein kinase 10, N-[3-({(4P)-4-[(3M)-1-tert-butyl-3-(3-hydroxyphenyl)-1H-pyrazol-4-yl]pyridin-2-yl}amino)propyl]-4-hydroxybenzene-1-sulfonamide 著者 Park, H, Mersal, K.I. 登録日 2022-09-30 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells. Eur.J.Med.Chem., 261, 2023

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