8EPV

2.2 A crystal structure of the lipocalin cat allergen Fel d 7

Summary for 8EPV

Entry DOI	10.2210/pdb8epv/pdb
Descriptor	Fel d 7 allergen, ACETATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	lipocalin, fatty acid binding protein, calyx, allergen
Biological source	Felis catus (domestic cat)
Total number of polymer chains	1
Total formula weight	18205.54
Authors	Min, J.,Pedersen, L.C.,Geoffrey, M.A. (deposition date: 2022-10-06, release date: 2023-04-05, Last modification date: 2024-11-13)
Primary citation	Min, J.,Foo, A.C.Y.,Gabel, S.A.,Perera, L.,DeRose, E.F.,Pomes, A.,Pedersen, L.C.,Mueller, G.A. Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7. Front Allergy, 4:1133412-1133412, 2023 Cited by PubMed Abstract: Pet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands. PubMed: 36960093 DOI: 10.3389/falgy.2023.1133412 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation