4IGR
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![BU of 4igr by Molmil](/molmil-images/mine/4igr) | Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist ZA302 | 分子名称: | (4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acid, CHLORIDE ION, Glutamate receptor, ... | 著者 | Larsen, A.P, Venskutonyte, R, Gajhede, M, Kastrup, J.S, Frydenvang, K. | 登録日 | 2012-12-18 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. J.Med.Chem., 56, 2013
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5CY0
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![BU of 5cy0 by Molmil](/molmil-images/mine/5cy0) | Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography | 分子名称: | GLYCEROL, Ts3 Toxin | 著者 | Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B. | 登録日 | 2015-07-29 | 公開日 | 2016-06-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angew.Chem.Int.Ed.Engl., 55, 2016
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1MJG
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![BU of 1mjg by Molmil](/molmil-images/mine/1mjg) | CRYSTAL STRUCTURE OF BIFUNCTIONAL CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE(CODH/ACS) FROM MOORELLA THERMOACETICA (F. CLOSTRIDIUM THERMOACETICUM) | 分子名称: | ACETATE ION, CARBON MONOXIDE DEHYDROGENASE BETA SUBUNIT, COPPER (I) ION, ... | 著者 | Doukov, T.I, Iverson, T.M, Seravalli, J, Ragsdale, S.W, Drennan, C.L. | 登録日 | 2002-08-27 | 公開日 | 2003-01-28 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA
synthase Science, 298, 2002
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7RMC
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![BU of 7rmc by Molmil](/molmil-images/mine/7rmc) | Yeast CTP Synthase (Ura7) filament bound to CTP at low pH | 分子名称: | CTP synthase 1, CYTIDINE-5'-TRIPHOSPHATE | 著者 | Hansen, J.M, Lynch, E.M, Farrell, D.P, DiMaio, F, Quispe, J, Kollman, J.M. | 登録日 | 2021-07-27 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation. Elife, 10, 2021
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7RE3
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![BU of 7re3 by Molmil](/molmil-images/mine/7re3) | SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC dimer | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | 著者 | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | 登録日 | 2021-07-12 | 公開日 | 2021-11-24 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29, 2022
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5H2K
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![BU of 5h2k by Molmil](/molmil-images/mine/5h2k) | A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 2 us after photoexcitation | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | 著者 | Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. | 登録日 | 2016-10-15 | 公開日 | 2016-12-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A three-dimensional movie of structural changes in bacteriorhodopsin Science, 354, 2016
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3AVS
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![BU of 3avs by Molmil](/molmil-images/mine/3avs) | Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 6A, ... | 著者 | Sengoku, T, Yokoyama, S. | 登録日 | 2011-03-07 | 公開日 | 2011-10-19 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A Genes Dev., 25, 2011
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5DI1
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![BU of 5di1 by Molmil](/molmil-images/mine/5di1) | MAP4K4 in complex with an inhibitor | 分子名称: | 4-{6-amino-5-[4-(methylsulfonyl)phenyl]pyridin-3-yl}phenol, Mitogen-activated protein kinase kinase kinase kinase 4 | 著者 | Liu, S. | 登録日 | 2015-08-31 | 公開日 | 2016-01-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment. Acs Med.Chem.Lett., 6, 2015
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8X3R
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4LDZ
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![BU of 4ldz by Molmil](/molmil-images/mine/4ldz) | Crystal structure of the full-length response regulator DesR in the active state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | 登録日 | 2013-06-25 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
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4LGS
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![BU of 4lgs by Molmil](/molmil-images/mine/4lgs) | Ricin A chain bound to camelid nanobody (VHH4) | 分子名称: | Camelid nanobody (VHH4), Ricin | 著者 | Rudolph, M.J, Cheung, J, Franklin, M, Burshteyn, F, Cassidy, M, Gary, E, Mantis, N. | 登録日 | 2013-06-28 | 公開日 | 2014-06-11 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies. J.Mol.Biol., 426, 2014
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3G15
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![BU of 3g15 by Molmil](/molmil-images/mine/3g15) | Crystal structure of human choline kinase alpha in complex with hemicholinium-3 and ADP | 分子名称: | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), ADENOSINE-5'-DIPHOSPHATE, Choline kinase alpha, ... | 著者 | Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) | 登録日 | 2009-01-29 | 公開日 | 2009-02-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. J.Biol.Chem., 285, 2010
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5H3S
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![BU of 5h3s by Molmil](/molmil-images/mine/5h3s) | apo form of GEMIN5-WD | 分子名称: | GLYCEROL, Gem-associated protein 5 | 著者 | Bharath, S.R, Tang, X, Song, H. | 登録日 | 2016-10-27 | 公開日 | 2016-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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5D3Y
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![BU of 5d3y by Molmil](/molmil-images/mine/5d3y) | Crystal Structure of the P-Rex1 PH domain with Inositol-(1,3,4,5)-Tetrakisphosphate Bound | 分子名称: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | 著者 | Cash, J.N, Tesmer, J.J.G. | 登録日 | 2015-08-06 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24, 2016
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1MPW
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![BU of 1mpw by Molmil](/molmil-images/mine/1mpw) | Molecular Recognition in (+)-a-Pinene Oxidation by Cytochrome P450cam | 分子名称: | (+)-alpha-Pinene, CYTOCHROME P450CAM, POTASSIUM ION, ... | 著者 | Bell, S.G, Chen, X, Sowden, R.J, Xu, F, Willams, J.N, Wong, L.-L, Rao, Z. | 登録日 | 2002-09-13 | 公開日 | 2002-10-09 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam J.Am.Chem.Soc., 125, 2003
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8WXE
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![BU of 8wxe by Molmil](/molmil-images/mine/8wxe) | Vgamma5Vdelta1 EH TCR-CD3 complex | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-28 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
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4LI1
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3FUR
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![BU of 3fur by Molmil](/molmil-images/mine/3fur) | Crystal Structure of PPARg in complex with INT131 | 分子名称: | 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide, CHLORIDE ION, Nuclear receptor coactivator 1, ... | 著者 | Wang, Z, Liu, J, Walker, N. | 登録日 | 2009-01-14 | 公開日 | 2009-06-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | INT131: a selective modulator of PPAR gamma. J.Mol.Biol., 386, 2009
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7RD1
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![BU of 7rd1 by Molmil](/molmil-images/mine/7rd1) | The Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25 | 分子名称: | Hexon protein, Hexon-interlacing protein, Penton protein, ... | 著者 | Baker, A.T, Boyd, R.J, Sarkar, D, Vermaas, J.V, Williams, D, Singharoy, A. | 登録日 | 2021-07-08 | 公開日 | 2021-12-15 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Sci Adv, 7, 2021
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4IJ2
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![BU of 4ij2 by Molmil](/molmil-images/mine/4ij2) | Human methemoglobin in complex with the second and third NEAT domains of IsdH from Staphylococcus aureus | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein H, ... | 著者 | Dickson, C.F, Jacques, D.A, Guss, J.M, Gell, D.A. | 登録日 | 2012-12-21 | 公開日 | 2013-12-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.24 Å) | 主引用文献 | Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus J.Biol.Chem., 289, 2014
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5H3T
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![BU of 5h3t by Molmil](/molmil-images/mine/5h3t) | m7G cap bound to GEMIN5-WD | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Gem-associated protein 5 | 著者 | Bharath, S.R, Tang, X, Song, H. | 登録日 | 2016-10-27 | 公開日 | 2016-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.571 Å) | 主引用文献 | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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2WLN
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![BU of 2wln by Molmil](/molmil-images/mine/2wln) | POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM | 分子名称: | POTASSIUM CHANNEL, POTASSIUM ION | 著者 | Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M. | 登録日 | 2009-06-24 | 公開日 | 2010-06-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | 主引用文献 | Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels. Cell(Cambridge,Mass.), 141, 2010
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4IDE
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![BU of 4ide by Molmil](/molmil-images/mine/4ide) | Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADP+ and EDHMF | 分子名称: | (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2012-12-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
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4LF0
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![BU of 4lf0 by Molmil](/molmil-images/mine/4lf0) | The E142D mutant of the amidase from Geobacillus pallidus | 分子名称: | Aliphatic amidase | 著者 | Sewell, B.T, Weber, B.W, Kimani, S.W, Cowan, D.A, Hunter, R, Venter, G.A, Gumbart, J.C, Thuku, R.N, Varsani, A. | 登録日 | 2013-06-26 | 公開日 | 2013-08-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J.Biol.Chem., 288, 2013
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3FWI
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![BU of 3fwi by Molmil](/molmil-images/mine/3fwi) | Ferric camphor bound Cytochrome P450cam containing a selenocysteine as the 5th heme ligand, tetragonal crystal form | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Schlichting, I, von Koenig, K, Aldag, C, Hilvert, D. | 登録日 | 2009-01-18 | 公開日 | 2009-03-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine. Proc.Natl.Acad.Sci.USA, 106, 2009
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