7RD1

The Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25

This is a non-PDB format compatible entry.

Summary for 7RD1

• Entry DOI: 10.2210/pdb7rd1/pdb
• EMDB information: 24408
• Descriptor: Pre-protein VI, Hexon protein, Penton protein, ... (6 entities in total)
• Functional Keywords: adenovirus, simian adenovirus, chimpanzee adenovirus, vaccine vector, dna virus, adv, chadv-y25, adenovirus y25, y25, viral vector, chadox1, chimp ad, dsdna virus, icosahedral, chimpanzee adenovirus y25, y-25, y 25, chadv, virus
• Biological source: Chimpanzee adenovirus Y25; More
• Total number of polymer chains: 32
• Total formula weight: 1821969.96

Authors

Baker, A.T.,Boyd, R.J.,Sarkar, D.,Vermaas, J.V.,Williams, D.,Singharoy, A. (deposition date: 2021-07-08, release date: 2021-12-15)

• Primary citation: Baker, A.T.,Boyd, R.J.,Sarkar, D.,Teijeira-Crespo, A.,Chan, C.K.,Bates, E.,Waraich, K.,Vant, J.,Wilson, E.,Truong, C.D.,Lipka-Lloyd, M.,Fromme, P.,Vermaas, J.,Williams, D.,Machiesky, L.,Heurich, M.,Nagalo, B.M.,Coughlan, L.,Umlauf, S.,Chiu, P.L.,Rizkallah, P.J.,Cohen, T.S.,Parker, A.L.,Singharoy, A.,Borad, M.J.; ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.; Sci Adv, 7:eabl8213-eabl8213, 2021; PubMed: 34851659; DOI: 10.1126/sciadv.abl8213

Experimental method

ELECTRON MICROSCOPY (3.07 Å)