PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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7XDB	Cryo-EM structure of SARS-CoV-2 Omicron Spike protein in complex with BA7208 fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7208 fab, ... 著者 Liu, Z, Liu, S, Gao, Y.Z. 登録日 2022-03-26 公開日 2023-03-01 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5. Cell Discov, 9, 2023
7XDL	Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7208 and BA7125 fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7125 fab, ... 著者 Liu, Z, Liu, S, Yuanzhu, G. 登録日 2022-03-27 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5. Cell Discov, 9, 2023
6PRW	CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS 分子名称: Propionyl-CoA carboxylase subunit beta, {4-[(6-chloroquinoxalin-2-yl)oxy]phenyl}acetic acid 著者 Reddy, M.C.M, Nian, Z, Michele, S.T.C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2019-07-11 公開日 2020-07-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.609 Å) 主引用文献 CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DEVERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS To Be Published
6PWH	Cystal structure of Myotoxin II from Bothrops moojeni co-crystallized with Varespladib (LY315920) 分子名称: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog 2, DIMETHYL SULFOXIDE 著者 Salvador, G.H.M, Fontes, M.R.M. 登録日 2019-07-23 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920). Sci Rep, 9, 2019
7UTY	First bromodomain of BRD4 liganded with compound 2c 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, prop-2-en-1-yl (5S)-1-ethyl-7-methyl-5-(4-methylphenyl)-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylate 著者 Schonbrunn, E, Chan, A. 登録日 2022-04-28 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains. Arch Pharm, 355, 2022
8HRD	Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant in complex with IMCAS74 Fab and W14 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS74 Fab heavy chain, IMCAS74 Fab light chain, ... 著者 Zhao, R.C, Wu, L.L, Han, P. 登録日 2022-12-15 公開日 2023-12-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
6R2S	The structure of Plasmodium vivax Duffy binding protein (PvDBP) bound to human antibody DB9 分子名称: Antibody DB9 heavy chain, Antibody DB9 light chain, Duffy receptor 著者 Barber, N.M, Higgins, M.K. 登録日 2019-03-18 公開日 2019-03-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody. Nat Microbiol, 4, 2019
7Y3O	Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody BIOLS56 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, Light chain of BIOLS56, ... 著者 Rao, X, Gao, F, Wu, Y, Gao, F. 登録日 2022-06-11 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
7Y3N	Crystal structure of SARS-CoV receptor binding domain in complex with human antibody BIOLS56 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BIOLS56, ... 著者 Rao, X, Chai, Y, Wu, Y, Gao, F. 登録日 2022-06-11 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4UV7	The complex structure of extracellular domain of EGFR and GC1118A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ... 著者 Yoo, J.H, Cho, H.S. 登録日 2014-08-05 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Gc1118, an Anti-Egfr Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity Against High-Affinity Egfr Ligands. Mol.Cancer Ther., 15, 2016
4HR3	Structure of a putative acyl-CoA dehydrogenase from Mycobacterium abscessus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative acyl-CoA dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-10-26 公開日 2012-11-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4I1Y	The structure of Cysteine synthase from Mycobacterium ulcerans Agy99 分子名称: CHLORIDE ION, Cysteine synthase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-11-21 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4IV6	X-ray crystal structure of an isovaleryl-CoA dehydrogenase from Mycobacterium smegmatis 分子名称: Acyl-CoA dehydrogenase FadE3, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-01-22 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4IZ9	Crystal structure of an acetate kinase from Mycobacterium avium bound to an unknown acid-ApCpp conjugate and manganese 分子名称: 1,2-ETHANEDIOL, Acetate kinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-01-29 公開日 2013-02-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4J3J	Crystal Structure of DPP-IV with Compound C3 分子名称: Dipeptidyl peptidase 4, N-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butyl]-6-(trifluoromethyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide 著者 Xiong, B, Zhu, L.R, Chen, D.Q, Zhao, Y.L, Jiang, F, Shen, J.K. 登録日 2013-02-05 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Design and synthesis of 4-(2,4,5-trifluorophenyl)butane-1,3-diamines as dipeptidyl peptidase IV inhibitors Chemmedchem, 8, 2013
4J5I	Crystal structure of an alpha-ketoglutarate-dependent taurine dioxygenase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, Alpha-ketoglutarate-dependent taurine dioxygenase, FE (III) ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-02-08 公開日 2013-02-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4JLV	Crystal structure of the chimerical protein CapA1B1 in complex with ADP-Mg 分子名称: ADENOSINE-5'-DIPHOSPHATE, C-terminal fragment of Membrane protein CapA1, Putative uncharacterized protein capB1, ... 著者 Gruszczyk, J, Olivares-Illana, V, Nourikyan, J, Fleurie, A, Bechet, E, Aumont-Nicaise, M, Gueguen-Chaignon, V, Morera, S, Grangeasse, C, Nessler, S. 登録日 2013-03-13 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus Plos One, 8, 2013
4HDT	Crystal structure of a Carnitinyl-CoA dehydratase from Mycobacterium thermoresistibile 分子名称: 3-hydroxyisobutyryl-CoA hydrolase, ACETATE ION, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-10-02 公開日 2012-10-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4IJN	Crystal structure of an acetate kinase from Mycobacterium smegmatis bound to AMP and sulfate 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Acetate kinase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-12-21 公開日 2013-01-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
1GYQ	CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD 分子名称: N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE) 著者 Suresh, S, Hol, W. 登録日 1999-03-05 公開日 1999-03-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase. Proc.Natl.Acad.Sci.USA, 96, 1999
4JMP	Crystal structure of the chimerical protein CapA2B2 分子名称: C-terminal fragment of CapA, Protein tyrosine kinase 著者 Olivares-Illana, V, Morera, S, Grangeasse, C, Nessler, S. 登録日 2013-03-14 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus Plos One, 8, 2013
4KAM	X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M 分子名称: O-acetylhomoserine sulfhydrylase MetC, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-04-22 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4HS3	Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, Envelope glycoprotein, ... 著者 Uchtenhagen, H, Boulanger, B, Hein, Z, Abualrous, E.T, Zacharias, M, Werner, J, Elliott, T, Springer, S, Achour, A. 登録日 2012-10-29 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Peptide-independent stabilization of MHC class I molecules breaches cellular quality control. J.Cell.Sci., 127, 2014
3V4O	Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor 分子名称: MALT1 Inhibitor, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 著者 Renatus, M, Wiesmann, C. 登録日 2011-12-15 公開日 2012-03-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Determinants of MALT1 Protease Activity. J.Mol.Biol., 419, 2012
3CWB	Chicken Cytochrome BC1 Complex inhibited by an iodinated analogue of the polyketide Crocacin-D 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, AZIDE ION, CARDIOLIPIN, ... 著者 Huang, L, Cromartie, T, Viner, R, Crowley, P.J, Berry, E.A. 登録日 2008-04-21 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D. Bioorg.Med.Chem., 16, 2008

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