7XDB

Cryo-EM structure of SARS-CoV-2 Omicron Spike protein in complex with BA7208 fab

Summary for 7XDB

• Entry DOI: 10.2210/pdb7xdb/pdb
• EMDB information: 33142
• Descriptor: BA7208 fab, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 9
• Total formula weight: 454750.55

Authors

Liu, Z.,Liu, S.,Gao, Y.Z. (deposition date: 2022-03-26, release date: 2023-03-01)

• Primary citation: Wang, Y.,Yan, A.,Song, D.,Dong, C.,Rao, M.,Gao, Y.,Qi, R.,Ma, X.,Wang, Q.,Xu, H.,Liu, H.,Han, J.,Duan, M.,Liu, S.,Yu, X.,Zong, M.,Feng, J.,Jiao, J.,Zhang, H.,Li, M.,Yu, B.,Wang, Y.,Meng, F.,Ni, X.,Li, Y.,Shen, Z.,Sun, B.,Shao, X.,Zhao, H.,Zhao, Y.,Li, R.,Zhang, Y.,Du, G.,Lu, J.,You, C.,Jiang, H.,Zhang, L.,Wang, L.,Dou, C.,Liu, Z.,Zhao, J.; Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.; Cell Discov, 9:3-3, 2023; PubMed: 36609558; DOI: 10.1038/s41421-022-00509-9

Experimental method

ELECTRON MICROSCOPY (2.62 Å)