7Y3O

Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody BIOLS56

Summary for 7Y3O

Entry DOI	10.2210/pdb7y3o/pdb
Descriptor	Heavy chain of BIOLS56, Light chain of BIOLS56, Spike protein S1, ... (5 entities in total)
Functional Keywords	sars-cov-2, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens More
Total number of polymer chains	3
Total formula weight	69492.45
Authors	Rao, X.,Gao, F.,Wu, Y.,Gao, F. (deposition date: 2022-06-11, release date: 2023-12-27)
Primary citation	Rao, X.,Zhao, R.,Tong, Z.,Guo, S.,Peng, W.,Liu, K.,Li, S.,Wu, L.,Tong, J.,Chai, Y.,Han, P.,Wang, F.,Jia, P.,Li, Z.,Zhao, X.,Li, D.,Zhang, R.,Zhang, X.,Zou, W.,Li, W.,Wang, Q.,Gao, G.F.,Wu, Y.,Dai, L.,Gao, F. Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120:e2314193120-e2314193120, 2023 Cited by PubMed: 38109549 DOI: 10.1073/pnas.2314193120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation