7Y3N

Crystal structure of SARS-CoV receptor binding domain in complex with human antibody BIOLS56

Summary for 7Y3N

• Entry DOI: 10.2210/pdb7y3n/pdb
• Descriptor: Spike protein S1, Heavy chain of BIOLS56, Light chain of BIOLS56, ... (5 entities in total)
• Functional Keywords: sars-cov, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus (SARS-CoV); More
• Total number of polymer chains: 9
• Total formula weight: 224695.45

Authors

Rao, X.,Chai, Y.,Wu, Y.,Gao, F. (deposition date: 2022-06-11, release date: 2023-12-27)

• Primary citation: Rao, X.,Zhao, R.,Tong, Z.,Guo, S.,Peng, W.,Liu, K.,Li, S.,Wu, L.,Tong, J.,Chai, Y.,Han, P.,Wang, F.,Jia, P.,Li, Z.,Zhao, X.,Li, D.,Zhang, R.,Zhang, X.,Zou, W.,Li, W.,Wang, Q.,Gao, G.F.,Wu, Y.,Dai, L.,Gao, F.; Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.; Proc.Natl.Acad.Sci.USA, 120:e2314193120-e2314193120, 2023; PubMed: 38109549; DOI: 10.1073/pnas.2314193120

Experimental method

X-RAY DIFFRACTION (2.97 Å)