6PWH

Cystal structure of Myotoxin II from Bothrops moojeni co-crystallized with Varespladib (LY315920)

Summary for 6PWH

Entry DOI	10.2210/pdb6pwh/pdb
Related	4YV5 6B80 6B84
Descriptor	Basic phospholipase A2 homolog 2, ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywords	myotoxin ii, mjtx-ii, lys49-pla2, varespladib, toxin
Biological source	Bothrops moojeni (Lance-headed viper)
Total number of polymer chains	2
Total formula weight	28741.48
Authors	Salvador, G.H.M.,Fontes, M.R.M. (deposition date: 2019-07-23, release date: 2019-12-04, Last modification date: 2023-10-11)
Primary citation	Salvador, G.H.M.,Gomes, A.A.S.,Bryan-Quiros, W.,Fernandez, J.,Lewin, M.R.,Gutierrez, J.M.,Lomonte, B.,Fontes, M.R.M. Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920). Sci Rep, 9:17203-17203, 2019 Cited by PubMed: 31748642 DOI: 10.1038/s41598-019-53755-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.749 Å)

Structure validation