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6FS9
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Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
分子名称: Baloxavir acid, CHLORIDE ION, MANGANESE (II) ION, ...
著者Cusack, S, Speranzini, V.
登録日2018-02-19
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
7QWJ
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Crystal structure of Glc7 phosphatase
分子名称: MANGANESE (II) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase PP1-2
著者Malhotra, K, Carminati, M, Bertolotti, A, Bellini, D.
登録日2022-01-25
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of Glc7 phosphatase
To Be Published
1JFI
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BU of 1jfi by Molmil
Crystal Structure of the NC2-TBP-DNA Ternary Complex
分子名称: 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ...
著者Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-06-20
公開日2001-07-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
Cell(Cambridge,Mass.), 106, 2001
6BCD
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BU of 6bcd by Molmil
Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
登録日2017-10-20
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
分子名称: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
著者Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
登録日2017-10-20
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
登録日2017-11-01
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
著者De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-05-15
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6Y7Y
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Fragments KCL_771 and KCL_802 in complex with MAP kinase p38-alpha
分子名称: (2-azanyl-2-adamantyl)methanol, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, 6-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]pyridine-3-sulfonamide, ...
著者De Nicola, G.F, Nichols, C.E.
登録日2020-03-02
公開日2020-03-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes.
J.Med.Chem., 63, 2020
7K5I
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BU of 7k5i by Molmil
SARS-COV-2 nsp1 in complex with human 40S ribosome
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Wang, L, Shi, M, Wu, H.
登録日2020-09-16
公開日2020-10-14
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism.
Biorxiv, 2020
3EVD
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BU of 3evd by Molmil
Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE
著者Thompson, A.A, Geiss, B.J, Peersen, O.B.
登録日2008-10-13
公開日2009-01-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Analysis of flavivirus NS5 methyltransferase cap binding.
J.Mol.Biol., 385, 2009
2JZ3
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BU of 2jz3 by Molmil
SOCS box elonginBC ternary complex
分子名称: Suppressor of cytokine signaling 3, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2
著者Babon, J.J, Sabo, J, Soetopo, A, Yao, S, Bailey, M.F, Zhang, J, Nicola, N.A, Norton, R.S.
登録日2007-12-27
公開日2008-09-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase
J.Mol.Biol., 381, 2008
6FS8
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BU of 6fs8 by Molmil
Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA)
分子名称: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein
著者Cusack, S, Speranzini, V.
登録日2018-02-19
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
7V2W
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BU of 7v2w by Molmil
protomer structure from the dimer of yeast THO complex
分子名称: Protein TEX1, THO complex subunit 2, THO complex subunit HPR1, ...
著者Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M.
登録日2021-08-10
公開日2022-07-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex.
Sci Bull (Beijing), 66, 2021
6R0C
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BU of 6r0c by Molmil
Human-D02 Nucleosome Core Particle with biotin-streptavidin label
分子名称: DNA (142-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
著者Pye, V.E, Wilson, M.D, Cherepanov, P, Costa, A.
登録日2019-03-12
公開日2019-09-25
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer.
Nat Commun, 10, 2019
7UQJ
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BU of 7uqj by Molmil
Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ATPgS and histone H3 tail in state II
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7, Histone H3, ...
著者Wang, F, Feng, X, Li, H.
登録日2022-04-19
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
J.Biol.Chem., 299, 2022
5FGP
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BU of 5fgp by Molmil
Crystal structure of D. melanogaster Pur-alpha repeat I-II in complex with DNA.
分子名称: CG1507-PB, isoform B, CHLORIDE ION, ...
著者Weber, J, Janowski, R, Niessing, D.
登録日2015-12-21
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.
Elife, 5, 2016
1F66
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BU of 1f66 by Molmil
2.6 A CRYSTAL STRUCTURE OF A NUCLEOSOME CORE PARTICLE CONTAINING THE VARIANT HISTONE H2A.Z
分子名称: HISTONE H2A.Z, HISTONE H2B, HISTONE H3, ...
著者Suto, R.K, Clarkson, M.J, Tremethick, D.J, Luger, K.
登録日2000-06-20
公開日2000-11-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a nucleosome core particle containing the variant histone H2A.Z.
Nat.Struct.Biol., 7, 2000
3KQN
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BU of 3kqn by Molmil
Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
分子名称: 5'-D(*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Gu, M, Rice, C.M.
登録日2009-11-17
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQU
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
分子名称: 5'-D(*T*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Gu, M, Rice, C.M.
登録日2009-11-17
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inaugural Article: Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
7XGC
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BU of 7xgc by Molmil
Crystal structure of influenza polymerase acidic subunit N-terminal domain crystallized by ammonium sulfate with glycan
分子名称: MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION
著者Guo, Y, Hoshino, T.
登録日2022-04-04
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Influence of Glycan Agents on Protein Crystallization with Ammonium Sulfate
Cryst.Growth Des., 2022
4KRF
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BU of 4krf by Molmil
Structure of Human Argonaute-1 let-7 complex
分子名称: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3')
著者Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
登録日2013-05-16
公開日2013-06-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
1YN6
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BU of 1yn6 by Molmil
Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase
分子名称: 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C.
登録日2005-01-23
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
4LFI
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BU of 4lfi by Molmil
Crystal structure of scCK2 alpha in complex with GMPPNP
分子名称: Casein kinase II subunit alpha, GLYCEROL, MANGANESE (II) ION, ...
著者Liu, H.
登録日2013-06-27
公開日2014-03-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
1HRH
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CRYSTAL STRUCTURE OF THE RIBONUCLEASE H DOMAIN OF HIV-1 REVERSE TRANSCRIPTASE
分子名称: RIBONUCLEASE H
著者Davies /II, J.F, Matthews, D.A.
登録日1991-03-06
公開日1992-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase.
Science, 252, 1991
7PRD
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Solution structure of the chimeric Nrd1-Nab3 heterodimerization domains
分子名称: Protein NRD1,HLJ1_G0022400.mRNA.1.CDS.1
著者Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M.
登録日2021-09-21
公開日2022-01-12
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis of Nrd1-Nab3 heterodimerization.
Life Sci Alliance, 5, 2022

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件を2024-08-07に公開中

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