2JZ3

SOCS box elonginBC ternary complex

Summary for 2JZ3

• Entry DOI: 10.2210/pdb2jz3/pdb
• Descriptor: Suppressor of cytokine signaling 3, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1 (3 entities in total)
• Functional Keywords: socs proteins, elongins, cytokine signaling, growth regulation, phosphoprotein, sh2 domain, signal transduction inhibitor, ubl conjugation pathway, nucleus, transcription, transcription regulation, signaling protein, transcription inhibitor-transcription complex, transcription inhibitor/transcription
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus (Probable): Q15370 P83940
• Total number of polymer chains: 3
• Total formula weight: 28564.39

Authors

Babon, J.J.,Sabo, J.,Soetopo, A.,Yao, S.,Bailey, M.F.,Zhang, J.,Nicola, N.A.,Norton, R.S. (deposition date: 2007-12-27, release date: 2008-09-23, Last modification date: 2011-07-13)

• Primary citation: Babon, J.J.,Sabo, J.K.,Soetopo, A.,Yao, S.,Bailey, M.F.,Zhang, J.-G.,Nicola, N.A.,Norton, R.S.; The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase; J.Mol.Biol., 381:928-940, 2008; PubMed: 18590740; DOI: 10.1016/j.jmb.2008.06.038

Experimental method

SOLUTION NMR