6BI7

Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions

Summary for 6BI7

• Entry DOI: 10.2210/pdb6bi7/pdb
• Related: 6BC8 6BCD
• Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, DNA polymerase zeta catalytic subunit (3 entities in total)
• Functional Keywords: dna damage tolerance, translesion dna synthesis, replication
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 117861.42

Authors

Rizzo, A.A.,Korzhnev, D.M.,Hao, B.,Li, Y. (deposition date: 2017-11-01, release date: 2018-08-01, Last modification date: 2023-10-04)

• Primary citation: Rizzo, A.A.,Vassel, F.M.,Chatterjee, N.,D'Souza, S.,Li, Y.,Hao, B.,Hemann, M.T.,Walker, G.C.,Korzhnev, D.M.; Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.; Proc. Natl. Acad. Sci. U.S.A., 115:E8191-E8200, 2018; PubMed: 30111544; DOI: 10.1073/pnas.1801149115

Experimental method

X-RAY DIFFRACTION (2.8 Å)