6BCD

Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)

Summary for 6BCD

• Entry DOI: 10.2210/pdb6bcd/pdb
• Related: 6BC8
• Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, DNA polymerase zeta catalytic subunit (3 entities in total)
• Functional Keywords: dna damage tolerance, translesion dna synthesis, replication
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 29365.15

Authors

Rizzo, A.A.,Hao, B.,Li, Y.,Korzhnev, D.M. (deposition date: 2017-10-20, release date: 2018-08-01, Last modification date: 2023-10-04)

• Primary citation: Rizzo, A.A.,Vassel, F.M.,Chatterjee, N.,D'Souza, S.,Li, Y.,Hao, B.,Hemann, M.T.,Walker, G.C.,Korzhnev, D.M.; Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.; Proc. Natl. Acad. Sci. U.S.A., 115:E8191-E8200, 2018; PubMed: 30111544; DOI: 10.1073/pnas.1801149115

Experimental method

X-RAY DIFFRACTION (1.43 Å)