7K5I

SARS-COV-2 nsp1 in complex with human 40S ribosome

Summary for 7K5I

EMDB information22681
Descriptor40S ribosomal protein S17, 40S ribosomal rRNA18S, 40S ribosomal protein S29, ... (38 entities in total)
Functional Keywordsnsp1, 40s, ribosome-viral protein complex, ribosome/viral protein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains36
Total molecular weight1242944.39
Authors
Wang, L.,Shi, M.,Wu, H. (deposition date: 2020-09-16, release date: 2020-10-14)
Primary citation
Shi, M.,Wang, L.,Fontana, P.,Vora, S.,Zhang, Y.,Fu, T.M.,Lieberman, J.,Wu, H.
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism.
Biorxiv, 2020
PubMed: 32995777 (PDB entries with the same primary citation)
DOI: 10.1101/2020.09.18.302901
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

Ramachandran outliersSidechain outliersRNA backbone 4.6% 28.6% 0.36MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
169963
PDB entries from 2020-10-14