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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7K5I

SARS-COV-2 nsp1 in complex with human 40S ribosome

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1R40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS17
2240S ribosomal rRNA18Spolymer1868602432.61GenBank (337376)Homo sapiens (Human)
3d40S ribosomal protein S29polymer566690.81UniProt (P62273)
Pfam (PF00253)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS14
4D40S ribosomal protein S3polymer24326729.41UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS3
5F40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS7
6K40S ribosomal protein S10polymer16518933.81UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS10
7M40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS12
8P40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (Human)RIG protein,Small ribosomal subunit protein uS19
9Q40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS9
10S40S ribosomal protein S18polymer15217759.81UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (Human)Ke-3,Ke3,Small ribosomal subunit protein uS13
11T40S ribosomal protein S19polymer14516091.61UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS19
12U40S ribosomal protein S20polymer11913398.81UniProt (P60866)
Pfam (PF00338)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS10
13Z40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS25
14c40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS28
15f40S ribosomal protein S27apolymer14917083.11UniProt (Q5RKT7)
Pfam (PF00240)
Pfam (PF01599)
UniProt (by SIFTS) (P62979)
In PDB		Homo sapiens (Human)Ubiquitin carboxyl extension protein 80,Ubiquitin-40S ribosomal protein S27a
16gReceptor of activated protein C kinase 1polymer31735115.71UniProt (P63244)
Pfam (PF00400)
In PDB		Homo sapiens (Human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
17A40S ribosomal protein SApolymer29532883.91UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (Human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
18B40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
19C40S ribosomal protein S2polymer29331376.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (Human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
20E40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Homo sapiens (Human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
21G40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (Human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
22H40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS7
23I40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS8
24J40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS4
25L40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS17
26N40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS15
27O40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS11
28V40S ribosomal protein S21polymer839124.41UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS21
29W40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS8
30X40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS12
31Y40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS24
32a40S ribosomal protein S26polymer10211777.01UniProt (P62854)
Pfam (PF01283)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS26
33b40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (Human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
34e40S ribosomal protein S30polymer596668.91UniProt (P62861)
Pfam (PF04758)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS30
35h60S ribosomal protein L41polymer253473.51UniProt (P62945)
Pfam (PF05162)
In PDB		Homo sapiens (Human)HG12,Large ribosomal subunit protein eL41
361Host translation inhibitor nsp1polymer18019801.31UniProt (P0DTD1)
Pfam (PF11501)
In PDB		Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)Leader protein, Non-structural protein 1, nsp1
372MAGNESIUM IONnon-polymer24.31Chemie (MG)
38d, f, aZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
2: 1 - 1869 (GenBank: 337376)
PDBExternal DatabaseDetails
C 1772G 1872conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains36
Total formula weight1242723.9
Non-Polymers*Number of molecules4
Total formula weight220.5
All*Total formula weight1242944.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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