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7MEP
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BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2(7S) - gp120, ...
著者Antanasijevic, A, Ward, A.B.
登録日2021-04-07
公開日2022-01-26
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献From structure to sequence: Antibody discovery using cryoEM.
Sci Adv, 8, 2022
8W0V
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Crystal structure of broadly neutralizing antibody hcab55 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Flyak, A.I, Wilcox, X.E.
登録日2024-02-14
公開日2024-03-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8W0W
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Crystal structure of broadly neutralizing antibody hcab64 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Flyak, A.I, Wilcox, X.E.
登録日2024-02-14
公開日2024-03-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8W0Y
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BU of 8w0y by Molmil
Crystal structure of broadly neutralizing antibody hcab17 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Flyak, A.I, Wilcox, X.E.
登録日2024-02-14
公開日2024-03-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8SLB
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BU of 8slb by Molmil
X-ray structure of CorA N-terminal domain in complex with conformation-specific synthetic antibody C12
分子名称: CHLORIDE ION, Cobalt/magnesium transport protein CorA, sAB C12 Heavy Chain, ...
著者Dominik, P.K, Erramilli, S.K, Reddy, B.G, Kossiakoff, A.A.
登録日2023-04-21
公開日2023-06-07
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
J.Mol.Biol., 435, 2023
6BKD
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BU of 6bkd by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3D heavy chain, Fab AR3D light chain, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2017-11-08
公開日2018-12-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies.
Sci Adv, 5, 2019
6VTW
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BU of 6vtw by Molmil
De novo protein design enables the precise induction of RSV-neutralizing antibodies
分子名称: 101F Fab Heavy Chain, 101F Fab Light Chain, S4_2.45
著者Jardetzky, T, Correia, B.
登録日2020-02-13
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Science, 368, 2020
6BKB
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BU of 6bkb by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3A heavy chain, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2017-11-08
公開日2018-12-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies.
Sci Adv, 5, 2019
6BKC
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BU of 6bkc by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3B heavy chain, Fab AR3B light chain, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2017-11-08
公開日2018-12-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies.
Sci Adv, 5, 2019
8W0X
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BU of 8w0x by Molmil
Crystal structure of broadly neutralizing antibody hcab40 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Flyak, A.I, Wilcox, X.E.
登録日2024-02-14
公開日2024-03-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
7Y72
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BU of 7y72 by Molmil
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)
分子名称: Fab E7 heavy chain, Fab E7 light chain, Spike glycoprotein
著者Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F.
登録日2022-06-21
公開日2023-08-02
最終更新日2023-08-09
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
7K24
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BU of 7k24 by Molmil
Murine polyomavirus pentavalent capsomer, subparticle reconstruction
分子名称: Capsid protein VP1
著者Goetschius, D.J, Hafenstein, S.L.
登録日2020-09-08
公開日2020-10-07
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Antibody escape by polyomavirus capsid mutation facilitates neurovirulence.
Elife, 9, 2020
7K23
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BU of 7k23 by Molmil
Murine polyomavirus hexavalent capsomer with 8A7H5 Fab, subparticle reconstruction
分子名称: 8A7H5 Fab heavy chain, 8A7H5 Fab light chain, Capsid protein VP1
著者Goetschius, D.J, Hafenstein, S.L.
登録日2020-09-08
公開日2020-10-07
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Antibody escape by polyomavirus capsid mutation facilitates neurovirulence.
Elife, 9, 2020
6DDR
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BU of 6ddr by Molmil
Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody
分子名称: Anti-MICA Fab fragment heavy chain clone 13A9, Anti-MICA Fab fragment light chain clone 13A9, GLYCEROL, ...
著者Matsumoto, M.L.
登録日2018-05-10
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.
MAbs, 11, 2019
7K25
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BU of 7k25 by Molmil
Murine polyomavirus hexavalent capsomer, subparticle reconstruction
分子名称: Capsid protein VP1
著者Goetschius, D.J, Hafenstein, S.L.
登録日2020-09-08
公開日2020-10-07
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Antibody escape by polyomavirus capsid mutation facilitates neurovirulence.
Elife, 9, 2020
6DDM
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BU of 6ddm by Molmil
Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody
分子名称: Anti-MICA Fab fragment heavy chain clone 1D5, Anti-MICA Fab fragment light chain clone 1D5, MHC class I polypeptide-related sequence A
著者Matsumoto, M.L.
登録日2018-05-10
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.
MAbs, 11, 2019
6DDV
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BU of 6ddv by Molmil
Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody
分子名称: Anti-MICA Fab fragment heavy chain clone 6E1, Anti-MICA Fab fragment light chain clone 6E1, MHC class I chain-related protein A
著者Matsumoto, M.L.
登録日2018-05-10
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.
MAbs, 11, 2019
8TH3
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BU of 8th3 by Molmil
Structure of AT118-H Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor
分子名称: AT118-H nanobody, Type-1 angiotensin II receptor, Soluble cytochrome b562 complex, ...
著者Skiba, M.A, Kruse, A.C.
登録日2023-07-13
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Antibodies expand the scope of angiotensin receptor pharmacology.
Nat.Chem.Biol., 2024
8TH4
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BU of 8th4 by Molmil
Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan
分子名称: AT118-L Nanobody, BAG2 Anti-BRIL Fab Heavy Chain, BAG2 Anti-BRIL Fab Light Chain, ...
著者Skiba, M.A, Kruse, A.C.
登録日2023-07-13
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Antibodies expand the scope of angiotensin receptor pharmacology.
Nat.Chem.Biol., 2024
8A1E
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BU of 8a1e by Molmil
Rabies virus glycoprotein in complex with Fab fragments of 17C7 and 1112-1 neutralizing antibodies
分子名称: Fab 1112-1 heavy chain variable domain, Fab 1112-1 light chain variable domain, Fab 17C7 heavy chain variable domain, ...
著者Ng, W.M, Fedosyuk, S, English, S, Augusto, G, Berg, A, Thorley, L, Haselon, A.S, Segireddy, R.R, Bowden, T.A, Douglas, A.D.
登録日2022-06-01
公開日2022-08-17
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies.
Cell Host Microbe, 30, 2022
8F5I
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BU of 8f5i by Molmil
SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1
分子名称: DH1057.1 HC, DH1057.1 LC, Specialized acyl carrier protein, ...
著者Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
登録日2022-11-14
公開日2023-10-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
7ZXF
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BU of 7zxf by Molmil
Pfs48/45 bound to monoclonal antibodies 10D8 and 85RF45.1
分子名称: 10D8 heavy chain, 10D8 light chain, 85RF45.1 heavy chain, ...
著者Ko, K.T, Lennartz, F.L, Higgins, M.K.
登録日2022-05-20
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.72 Å)
主引用文献Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
6WAQ
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BU of 6waq by Molmil
Crystal structure of the SARS-CoV-1 RBD bound by the cross-reactive single-domain antibody SARS VHH-72
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, nanobody SARS VHH-72
著者Wrapp, D, McLellan, J.S.
登録日2020-03-25
公開日2020-04-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
5TP3
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BU of 5tp3 by Molmil
Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4
分子名称: F-VHH-4
著者Wrapp, D, Gilman, M.S.A, McLellan, J.S.
登録日2016-10-19
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.874 Å)
主引用文献Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
6WAR
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BU of 6war by Molmil
Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, nanobody MERS VHH-55
著者Wrapp, D, Torres, G.M, McLellan, J.S.
登録日2020-03-25
公開日2020-04-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020

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件を2024-08-28に公開中

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