6WAQ

Crystal structure of the SARS-CoV-1 RBD bound by the cross-reactive single-domain antibody SARS VHH-72

Summary for 6WAQ

Entry DOI	10.2210/pdb6waq/pdb
Descriptor	nanobody SARS VHH-72, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	sars-cov-1, vhh, nanobody, rbd, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Lama glama More
Total number of polymer chains	4
Total formula weight	71680.57
Authors	Wrapp, D.,McLellan, J.S. (deposition date: 2020-03-25, release date: 2020-04-01, Last modification date: 2023-10-18)
Primary citation	Wrapp, D.,De Vlieger, D.,Corbett, K.S.,Torres, G.M.,Wang, N.,Van Breedam, W.,Roose, K.,van Schie, L.,Hoffmann, M.,Pohlmann, S.,Graham, B.S.,Callewaert, N.,Schepens, B.,Saelens, X.,McLellan, J.S. Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies. Cell, 181:1004-, 2020 Cited by PubMed: 32375025 DOI: 10.1016/j.cell.2020.04.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation